Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
csdCysteine desulfurase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. (411 aa)    
Predicted Functional Partners:
sufC
ATPase involved in Fe-S cluster formation SufC.
  
 0.989
sufB
FeS assembly protein SufB.
 
 0.986
APE_1061.1
Thioredoxin reductase; ApTR.
  
 
  0.915
metB
Cystathionine gamma-synthase.
    
 0.909
sufD
FeS assembly protein SufD.
 
 
 0.890
APE_1979.1
Conserved hypothetical protein.
 
  
 0.454
moaA
Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
  
 
 0.448
APE_0603
Molybdopterin converting factor; MoaD-MoaE fusion protein.
  
  
 0.417
cysS
cysteinyl-tRNA synthetase; CysRS; cysteine--tRNA ligase.
  
  
 0.414
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
Server load: low (14%) [HD]