Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
metBCystathionine gamma-synthase. (389 aa)    
Predicted Functional Partners:
APE_1223.1
Cystathionine beta-synthase; CBS.
 
 0.982
cysK
Cysteine synthase; Cysteine synthase that can also catalyze the synthesis of S- sulfo-L-cysteine from thiosulfate and O(3)-acetyl-L-serine, as well as the sulfhydrylation of L-serine by sulfide. Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.979
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
 
 0.968
APE_2050.1
Putative methylcobalamin:homocysteine methyltransferase; Putative methionine synthase.
  
 
 0.956
metE
Methylcobalamin:homocysteine methyltransferase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown (By similarity).
  
 
 0.955
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.935
hom
Homoserine dehydrogenase; HDH.
 
 
 0.923
APE_0595.1
Putative dehydrogenase.
  
 
 0.915
APE_1043.1
Putative dehydrogenase.
  
 
 0.915
metC
Cystathionine gamma-lyase.
  
  
0.909
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
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