node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argS | glyS | APE_1756 | APE_1639 | arginyl-tRNA synthetase; ArgRS; arginine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). | 0.830 |
argS | ileS | APE_1756 | APE_0374 | arginyl-tRNA synthetase; ArgRS; arginine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.987 |
argS | leuS | APE_1756 | APE_1015 | arginyl-tRNA synthetase; ArgRS; arginine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | leucyl-tRNA synthetase; LeuRS; leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.942 |
argS | metG | APE_1756 | APE_1129 | arginyl-tRNA synthetase; ArgRS; arginine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily. | 0.951 |
argS | pheS | APE_1756 | APE_2302.1 | arginyl-tRNA synthetase; ArgRS; arginine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | PheRS; phenylalanine--tRNA ligase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. | 0.815 |
argS | pheT | APE_1756 | APE_2305 | arginyl-tRNA synthetase; ArgRS; arginine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | PheRS; phenylalanine--tRNA ligase beta chain. | 0.890 |
argS | thrS2 | APE_1756 | APE_0117.1 | arginyl-tRNA synthetase; ArgRS; arginine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Misacylated tRNAthr hydrolase; Freestanding tRNA editing subunit of threonine--tRNA ligase, the catalytic subunit is probably AC Q9YDW0. Deacylates (edits) mischarged L-seryl-tRNA(Thr) in trans; has no activity on correctly charged L-threonyl-tRNA(Thr). Probably does not aminoacylate tRNA(Thr) (By similarity). Deacylates correctly charged glycyl-tRNA(Gly), but not glycyl-tRNA(Gly)(2'-dA76) (the terminal 2'-OH of tRNA adenine 76 has been dehydroxylated) nor the 2'-fluoro tRNA derivative, strongly suggesting the editing function is catalyzed by the 2'-OH of A76 of tRNA(Thr). | 0.579 |
argS | trpS | APE_1756 | APE_2461.1 | arginyl-tRNA synthetase; ArgRS; arginine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | tryptophanyl-tRNA synthetase; TrpRS; tryptophan--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.818 |
argS | tyrS | APE_1756 | APE_2074.1 | arginyl-tRNA synthetase; ArgRS; arginine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. | 0.878 |
argS | valS | APE_1756 | APE_1805.1 | arginyl-tRNA synthetase; ArgRS; arginine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner (By similarity); Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. | 0.883 |
glyS | argS | APE_1639 | APE_1756 | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). | arginyl-tRNA synthetase; ArgRS; arginine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.830 |
glyS | ileS | APE_1639 | APE_0374 | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.839 |
glyS | leuS | APE_1639 | APE_1015 | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). | leucyl-tRNA synthetase; LeuRS; leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.859 |
glyS | metG | APE_1639 | APE_1129 | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily. | 0.750 |
glyS | pheS | APE_1639 | APE_2302.1 | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). | PheRS; phenylalanine--tRNA ligase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. | 0.680 |
glyS | pheT | APE_1639 | APE_2305 | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). | PheRS; phenylalanine--tRNA ligase beta chain. | 0.623 |
glyS | thrS2 | APE_1639 | APE_0117.1 | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). | Misacylated tRNAthr hydrolase; Freestanding tRNA editing subunit of threonine--tRNA ligase, the catalytic subunit is probably AC Q9YDW0. Deacylates (edits) mischarged L-seryl-tRNA(Thr) in trans; has no activity on correctly charged L-threonyl-tRNA(Thr). Probably does not aminoacylate tRNA(Thr) (By similarity). Deacylates correctly charged glycyl-tRNA(Gly), but not glycyl-tRNA(Gly)(2'-dA76) (the terminal 2'-OH of tRNA adenine 76 has been dehydroxylated) nor the 2'-fluoro tRNA derivative, strongly suggesting the editing function is catalyzed by the 2'-OH of A76 of tRNA(Thr). | 0.883 |
glyS | trpS | APE_1639 | APE_2461.1 | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). | tryptophanyl-tRNA synthetase; TrpRS; tryptophan--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.712 |
glyS | tyrS | APE_1639 | APE_2074.1 | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. | 0.836 |
glyS | valS | APE_1639 | APE_1805.1 | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner (By similarity); Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. | 0.839 |