Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
APE_2086Conserved hypothetical protein. (331 aa)    
Predicted Functional Partners:
APE_2086a
Hypothetical protein.
  
  
 0.806
APE_2486.1
tRNA (m1A) methyltransferase.
 
  
 0.721
APE_0537.1
Conserved hypothetical protein.
  
  
 
0.621
APE_0603
Molybdopterin converting factor; MoaD-MoaE fusion protein.
  
 
 0.614
APE_2087.1
Putative aconitase, subunit.
 
     0.605
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
  
 0.592
APE_2325
Phospholipase A2/esterase.
       0.519
APE_2089
Putative aconitase, subunit; Belongs to the UPF0107 family.
       0.484
APE_1594
Putative ATP-dependent adenyltransferase; HesA/MoeB/ThiF family protein.
  
 
 0.473
rps8e
30S ribosomal protein S8e.
   
    0.463
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
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