Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
APE_2108acetyl-CoA acetyltransferase. (402 aa)    
Predicted Functional Partners:
APE_1484.1
3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA dehydratase.
 0.994
APE_1873.1
HMG-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family.
  
 0.990
gltA
Citrate synthase.
  
 0.960
acsA
Acetyl-coenzyme A synthetase.
  
 
 0.936
pdhC
Pyruvate dehydrogenase complex, E2 component; Dihydrolipoyllysine-residue acetyltransferase component.
  
 
 0.934
acsA-2
Acetyl-coenzyme A synthetase.
  
 
 0.928
acsA-3
Acetyl-coenzyme A synthetase.
  
 
 0.928
APE_2468.1
Putative propionate CoA-transferase.
    
 0.915
APE_0056.1
enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.906
APE_0591.1
enoyl-CoA hydratase/isomerase family protein.
  
 0.906
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
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