Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
APE_2219Aldehyde dehydrogenase, middle subunit. (292 aa)    
Predicted Functional Partners:
APE_2213
Aldehyde dehydrogenase, small subunit; Iron-sulfur subunit.
 
 0.999
APE_2216.1
Aldehyde dehydrogenase, large subunit.
 
 0.999
APE_0708.1
Aldehyde dehydrogenase, large subunit.
 
 0.993
APE_2227
CoxF homolog.
 
  
 0.862
APE_2223
PucB homolog.
  
  
 0.678
APE_2221.1
CoxE homolog.
 
     0.669
APE_0603
Molybdopterin converting factor; MoaD-MoaE fusion protein.
 
   
 0.604
APE_2225.1
CoxG homolog.
 
  
 0.587
APE_2220.1
CoxD homolog.
  
  
 0.529
APE_2212.1
Conserved hypothetical protein.
       0.462
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
Server load: low (10%) [HD]