| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APE_1458 | gcvH | APE_1458 | APE_0951.1 | Mercuric reductase; MerA; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.789 |
| APE_1458 | lipA | APE_1458 | APE_2344.1 | Mercuric reductase; MerA; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Lipoic acid synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.494 |
| APE_1458 | lipB | APE_1458 | APE_2341 | Mercuric reductase; MerA; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Lipoate-protein ligase; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. | 0.593 |
| APE_1458 | lipB-2 | APE_1458 | APE_2342.1 | Mercuric reductase; MerA; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Lipoate-protein ligase. | 0.490 |
| APE_1458 | pdhB | APE_1458 | APE_1674 | Mercuric reductase; MerA; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Pyruvate dehydrogenase E1 component, beta subunit. | 0.984 |
| APE_1458 | pdhC | APE_1458 | APE_1671 | Mercuric reductase; MerA; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Pyruvate dehydrogenase complex, E2 component; Dihydrolipoyllysine-residue acetyltransferase component. | 0.996 |
| APE_2347.1 | lipA | APE_2347.1 | APE_2344.1 | Hypothetical protein. | Lipoic acid synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.830 |
| APE_2347.1 | lipB | APE_2347.1 | APE_2341 | Hypothetical protein. | Lipoate-protein ligase; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. | 0.762 |
| APE_2347.1 | lipB-2 | APE_2347.1 | APE_2342.1 | Hypothetical protein. | Lipoate-protein ligase. | 0.773 |
| APE_2347.1 | pyrE | APE_2347.1 | APE_2349.1 | Hypothetical protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.449 |
| APE_2347.1 | pyrF | APE_2347.1 | APE_2348 | Hypothetical protein. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.535 |
| gcvH | APE_1458 | APE_0951.1 | APE_1458 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Mercuric reductase; MerA; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.789 |
| gcvH | lipA | APE_0951.1 | APE_2344.1 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoic acid synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.965 |
| gcvH | lipB | APE_0951.1 | APE_2341 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoate-protein ligase; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. | 0.824 |
| gcvH | lipB-2 | APE_0951.1 | APE_2342.1 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Lipoate-protein ligase. | 0.793 |
| gcvH | pdhC | APE_0951.1 | APE_1671 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Pyruvate dehydrogenase complex, E2 component; Dihydrolipoyllysine-residue acetyltransferase component. | 0.911 |
| gcvH | pdhD | APE_0951.1 | APE_1669.1 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyl dehydrogenase; Glycine cleavage system L protein; pyruvate dehydrogenase complex, E3 component. | 0.980 |
| lipA | APE_1458 | APE_2344.1 | APE_1458 | Lipoic acid synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Mercuric reductase; MerA; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.494 |
| lipA | APE_2347.1 | APE_2344.1 | APE_2347.1 | Lipoic acid synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Hypothetical protein. | 0.830 |
| lipA | gcvH | APE_2344.1 | APE_0951.1 | Lipoic acid synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.965 |
