Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
APE_2379Conserved hypothetical protein. (221 aa)    
Predicted Functional Partners:
rpl24e
50S ribosomal protein L24e; Binds to the 23S rRNA.
       0.603
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
       0.562
APE_0784.1
Conserved hypothetical protein.
 
     0.560
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
       0.535
oppA
Oligopeptide ABC transporter, oligopeptide binding protein.
  
     0.511
APE_0785.1
Conserved hypothetical protein.
 
    0.504
APE_2032.1
Conserved hypothetical protein.
 
     0.484
livK
Branched-chain amino acid ABC transporter, branched-chain amino acid-binding protein precursor.
 
 
   0.479
APE_0010.1
Putative amino acid transporter.
 
  
 0.461
rps28e
30S ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.
       0.440
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
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