Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
APE_2384Conserved hypothetical protein. (394 aa)    
Predicted Functional Partners:
APE_1484.1
3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA dehydratase.
  
 0.993
APE_1873.1
HMG-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family.
 
 0.991
APE_2389
Conserved hypothetical protein.
 
 
 0.985
APE_2390.1
Conserved hypothetical protein.
 
 
 0.984
acsA
Acetyl-coenzyme A synthetase.
  
 
 0.962
gltA
Citrate synthase.
  
 0.960
APE_2382.1
Conserved hypothetical protein.
 
  
 
0.944
pdhC
Pyruvate dehydrogenase complex, E2 component; Dihydrolipoyllysine-residue acetyltransferase component.
  
 
 0.934
acsA-2
Acetyl-coenzyme A synthetase.
  
 
 0.928
acsA-3
Acetyl-coenzyme A synthetase.
  
 
 0.928
Your Current Organism:
Aeropyrum pernix
NCBI taxonomy Id: 272557
Other names: A. pernix K1, Aeropyrum pernix K1, Aeropyrum pernix str. K1, Aeropyrum pernix strain K1
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