node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BH0101 | BH0102 | gene:10725941 | gene:10725942 | BH0101; unknown conserved protein. | Creatine kinase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. | 0.996 |
BH0101 | BH0104 | gene:10725941 | gene:10725944 | BH0101; unknown conserved protein. | DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. Belongs to the RecA family. RadA subfamily. | 0.643 |
BH0101 | BH0105 | gene:10725941 | gene:10725945 | BH0101; unknown conserved protein. | DNA integrity scanning protein DisA; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | 0.610 |
BH0101 | BH0106 | gene:10725941 | gene:10725946 | BH0101; unknown conserved protein. | BH0106; unknown conserved protein. | 0.650 |
BH0101 | BH2494 | gene:10725941 | gene:10728392 | BH0101; unknown conserved protein. | Transcription factor FapR; Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism. | 0.537 |
BH0101 | BH3769 | gene:10725941 | gene:10729682 | BH0101; unknown conserved protein. | Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.662 |
BH0101 | clpC | gene:10725941 | gene:10725943 | BH0101; unknown conserved protein. | Class III stress response-related ATPase; BH0103; Belongs to the ClpA/ClpB family. | 0.960 |
BH0101 | clpE | gene:10725941 | gene:10728077 | BH0101; unknown conserved protein. | ATP-dependent proteinase; BH2179; Belongs to the ClpA/ClpB family. | 0.651 |
BH0101 | ctsR | gene:10725941 | gene:10725940 | BH0101; unknown conserved protein. | Transcriptional repressor of class III stress genes; BH0100; Belongs to the CtsR family. | 0.979 |
BH0102 | BH0101 | gene:10725942 | gene:10725941 | Creatine kinase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. | BH0101; unknown conserved protein. | 0.996 |
BH0102 | BH0104 | gene:10725942 | gene:10725944 | Creatine kinase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. | DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. Belongs to the RecA family. RadA subfamily. | 0.743 |
BH0102 | BH0105 | gene:10725942 | gene:10725945 | Creatine kinase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. | DNA integrity scanning protein DisA; Participates in a DNA-damage check-point that is active prior to asymmetric division when DNA is damaged. DisA forms globular foci that rapidly scan along the chromosomes during sporulation, searching for lesions. When a lesion is present, DisA pauses at the lesion site. This triggers a cellular response that culminates in a temporary block in sporulation initiation. | 0.612 |
BH0102 | BH0106 | gene:10725942 | gene:10725946 | Creatine kinase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. | BH0106; unknown conserved protein. | 0.643 |
BH0102 | BH0107 | gene:10725942 | gene:10725947 | Creatine kinase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.454 |
BH0102 | BH2494 | gene:10725942 | gene:10728392 | Creatine kinase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. | Transcription factor FapR; Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism. | 0.488 |
BH0102 | BH3769 | gene:10725942 | gene:10729682 | Creatine kinase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. | Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. | 0.709 |
BH0102 | clpC | gene:10725942 | gene:10725943 | Creatine kinase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. | Class III stress response-related ATPase; BH0103; Belongs to the ClpA/ClpB family. | 0.988 |
BH0102 | clpE | gene:10725942 | gene:10728077 | Creatine kinase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. | ATP-dependent proteinase; BH2179; Belongs to the ClpA/ClpB family. | 0.723 |
BH0102 | ctsR | gene:10725942 | gene:10725940 | Creatine kinase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity. | Transcriptional repressor of class III stress genes; BH0100; Belongs to the CtsR family. | 0.965 |
BH0104 | BH0101 | gene:10725944 | gene:10725941 | DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. Belongs to the RecA family. RadA subfamily. | BH0101; unknown conserved protein. | 0.643 |