STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sigARNA polymerase major sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (372 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.980
rpoB
DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.974
rpoC
DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.957
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
  
 0.955
rpoZ
DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
   
 
 0.911
nusG
Transcriptional antitermination factor; Participates in transcription elongation, termination and antitermination.
  
  
 0.896
BH3496
Transcriptional regulator of multidrug-efflux transporter genes.
  
 
 0.895
BH4046
Transcriptional regulator of the bltD operon; BH4046; incomplete.
  
 
 0.895
BH4047
BH4047; unknown conserved protein in B. subtilis.
  
 
 0.895
nusA
Transcriptional terminator; Participates in both transcription termination and antitermination.
 
 
 0.873
Your Current Organism:
Bacillus halodurans
NCBI taxonomy Id: 272558
Other names: B. halodurans C-125, Bacillus halodurans C-125, Bacillus halodurans str. C-125, Bacillus halodurans strain C-125
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.