STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hutUUroconase (urocanate hydratase); Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (559 aa)    
Predicted Functional Partners:
hutH
Histidase (histidine ammonia-lyase); BH1982; Belongs to the PAL/histidase family.
 
 0.999
hutI
Imidazolonepropionase (imidazolone-5-propionate hydrolase); BH1984; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
 
 0.999
hutG
Formiminoglutamase (formiminoglutamate hydrolase); Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
 
  
 0.987
glpP
Transcriptional antiterminator of glycerol uptake operon; Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA.
      
 0.761
BH2935
Aryldialkylphosphatase.
  
  
 0.711
BH3008
BH3008; unknown conserved protein.
  
  
 0.711
hutP
Transcriptional activator of the histidine utilization operon; Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization; Belongs to the HutP family.
 
  
 0.681
pyrR
Transcriptional attenuation of the pyrimidine operon/uracil phosphoribosyl transferase; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
      
 0.618
BH1986
BH1986; unknown conserved protein.
       0.593
Your Current Organism:
Bacillus halodurans
NCBI taxonomy Id: 272558
Other names: B. halodurans C-125, Bacillus halodurans C-125, Bacillus halodurans str. C-125, Bacillus halodurans strain C-125
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