node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BH0376 | BH3106 | gene:10726229 | gene:10729018 | DNA mismatch repair protein. | DNA mismatch repair protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. | 0.913 |
BH0376 | mulT | gene:10726229 | gene:10728266 | DNA mismatch repair protein. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.673 |
BH0376 | mutS | gene:10726229 | gene:10728267 | DNA mismatch repair protein. | DNA mismatch repair protein (mismatch recognition step); This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.941 |
BH0376 | polA | gene:10726229 | gene:10729065 | DNA mismatch repair protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.499 |
BH1607 | BH2180 | gene:10727505 | gene:10728078 | ATP-dependent DNA helicase. | 5'-3' exonuclease; 5'-3' exonuclease acting preferentially on double-stranded DNA. | 0.886 |
BH1607 | dnaN | gene:10727505 | gene:10725817 | ATP-dependent DNA helicase. | DNA polymerase III (beta subunit); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation o [...] | 0.819 |
BH1607 | mulT | gene:10727505 | gene:10728266 | ATP-dependent DNA helicase. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.892 |
BH1607 | mutS | gene:10727505 | gene:10728267 | ATP-dependent DNA helicase. | DNA mismatch repair protein (mismatch recognition step); This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.835 |
BH1607 | polA | gene:10727505 | gene:10729065 | ATP-dependent DNA helicase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.936 |
BH1607 | topA | gene:10727505 | gene:10728365 | ATP-dependent DNA helicase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.971 |
BH2180 | BH1607 | gene:10728078 | gene:10727505 | 5'-3' exonuclease; 5'-3' exonuclease acting preferentially on double-stranded DNA. | ATP-dependent DNA helicase. | 0.886 |
BH2180 | dnaN | gene:10728078 | gene:10725817 | 5'-3' exonuclease; 5'-3' exonuclease acting preferentially on double-stranded DNA. | DNA polymerase III (beta subunit); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation o [...] | 0.940 |
BH2180 | mulT | gene:10728078 | gene:10728266 | 5'-3' exonuclease; 5'-3' exonuclease acting preferentially on double-stranded DNA. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.884 |
BH2180 | mutS | gene:10728078 | gene:10728267 | 5'-3' exonuclease; 5'-3' exonuclease acting preferentially on double-stranded DNA. | DNA mismatch repair protein (mismatch recognition step); This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.888 |
BH2180 | polA | gene:10728078 | gene:10729065 | 5'-3' exonuclease; 5'-3' exonuclease acting preferentially on double-stranded DNA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.633 |
BH2180 | topA | gene:10728078 | gene:10728365 | 5'-3' exonuclease; 5'-3' exonuclease acting preferentially on double-stranded DNA. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.782 |
BH2367 | miaA | gene:10728265 | gene:10728264 | BH2367; unknown conserved protein. | tRNA isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.676 |
BH2367 | mulT | gene:10728265 | gene:10728266 | BH2367; unknown conserved protein. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.805 |
BH2367 | mutS | gene:10728265 | gene:10728267 | BH2367; unknown conserved protein. | DNA mismatch repair protein (mismatch recognition step); This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.762 |
BH3106 | BH0376 | gene:10729018 | gene:10726229 | DNA mismatch repair protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. | DNA mismatch repair protein. | 0.913 |