node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BH0520 | recF | gene:10726373 | gene:10725819 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | DNA repair and genetic recombination; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity). | 0.580 |
BH0520 | recN | gene:10726373 | gene:10728676 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | DNA repair and genetic recombination; May be involved in recombinational repair of damaged DNA. | 0.678 |
BH0924 | BH1369 | gene:10726798 | gene:10727263 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.856 |
BH0924 | lexA | gene:10726798 | gene:10728254 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | Transcriptional repressor of the SOS regulon; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.438 |
BH0924 | recA | gene:10726798 | gene:10728281 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | Multifunctional protein involved in homologous recombination; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.964 |
BH0924 | recF | gene:10726798 | gene:10725819 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | DNA repair and genetic recombination; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity). | 0.724 |
BH0924 | recN | gene:10726798 | gene:10728676 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | DNA repair and genetic recombination; May be involved in recombinational repair of damaged DNA. | 0.799 |
BH0924 | ruvA | gene:10726798 | gene:10727118 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.754 |
BH0924 | ruvB | gene:10726798 | gene:10727119 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | Holliday junction DNA helicase (DNA-binding protein); The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.687 |
BH1369 | BH0924 | gene:10727263 | gene:10726798 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.856 |
BH1369 | BH2783 | gene:10727263 | gene:10728683 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | Exodeoxyribonuclease VII (large subunit); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.430 |
BH1369 | lexA | gene:10727263 | gene:10728254 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | Transcriptional repressor of the SOS regulon; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.429 |
BH1369 | recA | gene:10727263 | gene:10728281 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | Multifunctional protein involved in homologous recombination; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.622 |
BH1369 | recF | gene:10727263 | gene:10725819 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | DNA repair and genetic recombination; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity). | 0.745 |
BH1369 | recN | gene:10727263 | gene:10728676 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | DNA repair and genetic recombination; May be involved in recombinational repair of damaged DNA. | 0.749 |
BH1369 | ruvA | gene:10727263 | gene:10727118 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.716 |
BH1369 | ruvB | gene:10727263 | gene:10727119 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | Holliday junction DNA helicase (DNA-binding protein); The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.727 |
BH2783 | BH1369 | gene:10728683 | gene:10727263 | Exodeoxyribonuclease VII (large subunit); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.430 |
BH2783 | recN | gene:10728683 | gene:10728676 | Exodeoxyribonuclease VII (large subunit); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | DNA repair and genetic recombination; May be involved in recombinational repair of damaged DNA. | 0.683 |
BH2783 | ruvA | gene:10728683 | gene:10727118 | Exodeoxyribonuclease VII (large subunit); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | Holliday junction DNA helicase; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.534 |