node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BH0216 | BH0779 | gene:10726056 | gene:10726653 | Pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase). | Dihydrolipoamide dehydrogenase. | 0.914 |
BH0216 | BH2764 | gene:10726056 | gene:10728664 | Pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase). | Dihydrolipoamide dehydrogenase. | 0.912 |
BH0216 | BH2814 | gene:10726056 | gene:10728714 | Pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase). | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.937 |
BH0216 | BH2815 | gene:10726056 | gene:10728715 | Pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase). | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.934 |
BH0216 | BH2816 | gene:10726056 | gene:10728716 | Pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase). | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.962 |
BH0216 | BH3484 | gene:10726056 | gene:10729397 | Pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase). | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.973 |
BH0216 | acoL | gene:10726056 | gene:10727723 | Pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase). | Acetoin dehydrogenase E3 component (dihydrolipoamide dehydroge); BH1825. | 0.912 |
BH0216 | glyA | gene:10726056 | gene:10729678 | Pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase). | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.934 |
BH0779 | BH0216 | gene:10726653 | gene:10726056 | Dihydrolipoamide dehydrogenase. | Pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase). | 0.914 |
BH0779 | BH2764 | gene:10726653 | gene:10728664 | Dihydrolipoamide dehydrogenase. | Dihydrolipoamide dehydrogenase. | 0.908 |
BH0779 | BH2814 | gene:10726653 | gene:10728714 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.940 |
BH0779 | BH2815 | gene:10726653 | gene:10728715 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.938 |
BH0779 | BH2816 | gene:10726653 | gene:10728716 | Dihydrolipoamide dehydrogenase. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.965 |
BH0779 | BH3484 | gene:10726653 | gene:10729397 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.972 |
BH0779 | acoL | gene:10726653 | gene:10727723 | Dihydrolipoamide dehydrogenase. | Acetoin dehydrogenase E3 component (dihydrolipoamide dehydroge); BH1825. | 0.909 |
BH0779 | glyA | gene:10726653 | gene:10729678 | Dihydrolipoamide dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.937 |
BH1629 | BH2814 | gene:10727527 | gene:10728714 | BH1629; unknown conserved protein. | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.553 |
BH1629 | BH2815 | gene:10727527 | gene:10728715 | BH1629; unknown conserved protein. | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.463 |
BH1629 | BH2816 | gene:10727527 | gene:10728716 | BH1629; unknown conserved protein. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.959 |
BH1629 | BH3484 | gene:10727527 | gene:10729397 | BH1629; unknown conserved protein. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. | 0.508 |