STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSL0002Putative membrane protein; Similar to Ralstonia solanacearum hypothetical transmembrane protein RSC3299 or RS02528 SWALL:Q8XU94 (EMBL:AL646074) (407 aa) fasta scores: E(): 2.8e-63, 43.31% id in 404 aa. N-terminus is weakly similar to the N-terminal region of Escherichia coli glutathione-regulated potassium-efflux system protein KefB or TrkB SWALL:KEFB_ECOLI (SWALL:P45522) (601 aa) fasta scores: E(): 0.0018, 26.94% id in 360 aa. (404 aa)    
Predicted Functional Partners:
BPSL0001
Conserved hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
 
     0.839
BPSL2165
Putative membrane protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.
  
     0.694
BPSL0995
Putative membrane protein; Similar to Ralstonia solanacearum putative signal peptide protein rsc2383 or rs06185 SWALL:Q8XWT7 (EMBL:AL646069) (1299 aa) fasta scores: E(): 3.6e-120, 42.81% id in 1371 aa, and to Neisseria meningitidis hypothetical protein nmb2135 SWALL:Q9JXB6 (EMBL:AE002561) (1405 aa) fasta scores: E(): 8.4e-29, 26.91% id in 1475 aa.
  
     0.672
BPSL2494
Putative membrane protein; Similar to Ralstonia solanacearum probable transmembrane protein rsc0929 or rs04485 SWALL:Q8Y0W4 (EMBL:AL646061) (151 aa) fasta scores: E(): 1.1e-29, 56.66% id in 150 aa.
 
     0.669
BPSL2644
Putative exported protein; Similar to Ralstonia solanacearum probable transmembrane protein rsc0700 or rs01605 SWALL:Q8Y1J0 (EMBL:AL646060) (204 aa) fasta scores: E(): 1.3e-26, 46.39% id in 194 aa.
  
     0.669
BPSL1194
Putative membrane protein; Similar to Ralstonia solanacearum probable transmembrane protein rsc2079 or rs03644 SWALL:Q8XXN4 (EMBL:AL646068) (146 aa) fasta scores: E(): 2.5e-16, 50% id in 140 aa.
  
     0.664
BPSL2667
Similar to Escherichia coli lipopolysaccharide biosynthesis protein WzxC or Wzx or b2046 SWALL:WZXC_ECOLI (SWALL:P77377) (492 aa) fasta scores: E(): 0.012, 22.33% id in 412 aa, Ralstonia solanacearum putative lipopolysaccharide O-side chain biosynthesis transmembrane protein rsc0686 or rs01591 SWALL:Q8Y1K4 (EMBL:AL646060) (422 aa) fasta scores: E(): 1.6e-26, 28.7% id in 425 aa and to Salmonella typhimurium O-antigen translocase in LPS biosyntesis WzxE or stm3926 SWALL:Q9L6Q9 (EMBL:AE008883) (416 aa) fasta scores: E(): 5.7e-08, 24.39% id in 410 aa.
  
    0.643
BPSL3403
Putative ATP synthase protein I AtpI; Note possible downstream alternative start codons. Full length similarity to Ralstonia solanacearum hypothetical transmembrane protein Rsc3324 or Rs02554 SWALL:Q8XU69 (EMBL:AL646074) (190 aa) fasta scores: E(): 5.1e-17, 39.34% id in 183 aa. N-terminally truncated version similar to Pseudomonas aeruginosa ATP synthase protein I AtpI or Pa5561 SWALL:Q9HT13 (EMBL:AE004967) (126 aa) fasta scores: E(): 3.9e-06, 36.2% id in 116 aa.
  
     0.635
BPSL2253
Putative exported protein; Similar to Ralstonia solanacearum probable transmembrane protein rsc1150 or rs04601 SWALL:Q8Y094 (EMBL:AL646063) (354 aa) fasta scores: E(): 4.6e-33, 36.13% id in 357 aa. CDS is extended at the C-terminus in comparison to R. solanacearum protein.
 
     0.631
gspL
Previously sequenced as Burkholderia pseudomallei general secretory pathway protein L GspL SWALL:Q9ZF77 (EMBL:AF110185) (444 aa) fasta scores: E(): 3.1e-79, 95.67% id in 462 aa. CDS is extended at the N-terminus in comparison to the previously sequenced protein. CDS also contains extra internal amino acid residues (229 to 246) relative to the previously sequenced protein. C-terminal region is similar to Pseudomonas aeruginosa general secretion pathway protein L XcpY SWALL:GSPL_PSEAE (SWALL:P25060) (382 aa) fasta scores: E(): 0.75, 24.33% id in 378 aa.
  
     0.630
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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