Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gspCPutative general secretory pathway protein; Previously sequenced as Burkholderia pseudomallei protein essential for the secretion of exoproducts GspC SWALL:Q9ZF83 (EMBL:AF110185) (136 aa) fasta scores: E(): 8.2e-48, 100% id in 136 aa. Similar to the N-terminal region of Ralstonia solanacearum putative general secretion pathway related transmembrane protein GspC or RSC3105 or RS00558 SWALL:Q8XUT0 (EMBL:AL646073) (228 aa) fasta scores: E(): 8.9e-12, 42.33% id in 137 aa. (136 aa)    
Predicted Functional Partners:
gspG
Previously sequenced as Burkholderia pseudomallei general secretory pathway protein G GspG SWALL:Q9ZF82 (EMBL:AF110185) (150 aa) fasta scores: E(): 2.1e-58, 100% id in 150 aa. Similar to Erwinia carotovora general secretion pathway protein G precursor OutG SWALL:GSPG_ERWCA (SWALL:P31586) (156 aa) fasta scores: E(): 2.5e-27, 53.57% id in 140 aa.
  
  
 0.860
gspK
Previously sequenced as Burkholderia pseudomallei general secretory pathway protein K GspK SWALL:Q9ZF78 (EMBL:AF110185) (356 aa) fasta scores: E(): 9.2e-126, 99.15% id in 356 aa. Similar to Erwinia carotovora general secretion pathway protein K OutK SWALL:GSPK_ERWCA (SWALL:P31706) (328 aa) fasta scores: E(): 0.59, 24.63% id in 345 aa.
  
  
 0.843
gspJ
General secretory pathway protein J; N-terminal region is identical to the previously sequenced Burkholderia pseudomallei general secretory pathway protein J GspJ SWALL:Q9ZF79 (EMBL:AF110185) (217 aa) fasta scores: E(): 3.3e-70, 100% id in 192 aa. CDS differs from the previously sequenced protein in the C-terminal region. C-terminal region is similar to Burkholderia cepacia general secretory pathway protein GspJ SWALL:Q9F1P4 (EMBL:AB050004) (222 aa) fasta scores: E(): 3e-60, 75.67% id in 222 aa.
  
  
 0.827
gspL
Previously sequenced as Burkholderia pseudomallei general secretory pathway protein L GspL SWALL:Q9ZF77 (EMBL:AF110185) (444 aa) fasta scores: E(): 3.1e-79, 95.67% id in 462 aa. CDS is extended at the N-terminus in comparison to the previously sequenced protein. CDS also contains extra internal amino acid residues (229 to 246) relative to the previously sequenced protein. C-terminal region is similar to Pseudomonas aeruginosa general secretion pathway protein L XcpY SWALL:GSPL_PSEAE (SWALL:P25060) (382 aa) fasta scores: E(): 0.75, 24.33% id in 378 aa.
     
 0.815
gspI
Previously sequenced as Burkholderia pseudomallei general secretory pathway protein I GspI SWALL:Q9ZF80 (EMBL:AF110185) (134 aa) fasta scores: E(): 1.1e-49, 100% id in 134 aa. Similar to Pseudomonas aeruginosa general secretion pathway protein I precursor XcpV or PddC SWALL:GSPI_PSEAE (SWALL:Q00516) (129 aa) fasta scores: E(): 0.00019, 37% id in 100 aa.
  
  
 0.806
gspH
Previously sequenced as Burkholderia pseudomallei general secretory pathway protein H GspH SWALL:Q9ZF81 (EMBL:AF110185) (159 aa) fasta scores: E(): 4.1e-60, 100% id in 159 aa. Similar to Erwinia carotovora general secretion pathway protein G precursor OutG SWALL:GSPG_ERWCA (SWALL:P31586) (156 aa) fasta scores: E(): 0.38, 29.73% id in 111 aa.
  
  
 0.785
gspM
Previously sequenced as Burkholderia pseudomallei general secretory pathway protein M GspM SWALL:Q9ZF76 (EMBL:AF110185) (168 aa) fasta scores: E(): 3.3e-58, 100% id in 168 aa. Similar to Erwinia carotovora general secretion pathway protein M OutM SWALL:GSPM_ERWCA (SWALL:P31709) (164 aa) fasta scores: E(): 0.00098, 26.58% id in 158 aa.
     
 0.727
gspD
Previously sequenced as Burkholderia pseudomallei general secretory pathway protein D GspD SWALL:Q9ZF86 (EMBL:AF110185) (750 aa) fasta scores: E(): 0, 99.86% id in 750 aa. CDS is extended at the N-terminus in comparison to the previously sequenced protein. Similar to Erwinia chrysanthemi general secretion pathway protein D precursor OutD SWALL:GSPD_ERWCH (SWALL:P31700) (712 aa) fasta scores: E(): 2.5e-21, 33.23% id in 680 aa.
  
 
 0.678
sctC
Putative type III secretion system protein; Almost identical to the previously sequenced Burkholderia pseudomallei typeIII secretion-system associated protein SctC SWALL:Q93L02 (EMBL:AF074878) (588 aa) fasta scores: E(): 7.7e-207, 99.49% id in 588 aa. Similar to Ralstonia solanacearum hypersensitivity response secretion protein HrpA precursor HrpA or HrcC or rsp0874 or rs01645 SWALL:HRPA_RALSO (SWALL:Q52498) (568 aa) fasta scores: E(): 1.3e-84, 45.58% id in 577 aa, and to Burkholderia cepacia genomovar III BcsCC SWALL:Q8VP21 (EMBL:AY028431) (681 aa) fasta scores: E(): 2.9e-39, 37.1% id [...]
  
 
 0.678
bsaO
Type III secretion system protein; Similar to Salmonella typhimurium InvG protein precursor InvG or stm2898 SWALL:INVG_SALTY (SWALL:P35672) (562 aa) fasta scores: E(): 1.8e-22, 44.5% id in 519 aa, and to Escherichia coli O157:H7 type III secretion apparatus protein z4197 or ecs3733 SWALL:Q8X6D6 (EMBL:AE005515) (567 aa) fasta scores: E(): 4e-36, 40.81% id in 517 aa.
  
 
 0.678
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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