STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSL0180HpcH/HpaI aldolase family protein; Similar to Escherichia coli 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase HpcH or HpaI SWALL:HPAI_ECOLI (SWALL:Q47098) (262 aa) fasta scores: E(): 1.6e-31, 44.57% id in 249 aa, and to Escherichia coli 2-dehydro-3-deoxyglucarate aldolase GarL SWALL:GARL_ECOLI (SWALL:P23522) (256 aa) fasta scores: E(): 6e-32, 46.21% id in 238 aa; Belongs to the HpcH/HpaI aldolase family. (261 aa)    
Predicted Functional Partners:
hpcG
Similar to Escherichia coli 2-oxo-hepta-3-ene-1,7-dioic acid hydratase HpcG SWALL:HPCG_ECOLI (SWALL:P42270) (264 aa) fasta scores: E(): 3.3e-74, 70.3% id in 266 aa, and to Salmonella typhimurium, and Salmonella typhi 4-hydroxyphenylacetate catabolism stm1105 or sty1139 SWALL:Q8XGD0 (EMBL:AE008748) (267 aa) fasta scores: E(): 1.4e-80, 74.06% id in 266 aa.
  
 0.926
glxR
Similar to Escherichia coli 2-hydroxy-3-oxopropionate reductase GlxR or GlxB1 or b0509 SWALL:GLXR_ECOLI (SWALL:P77161) (292 aa) fasta scores: E(): 8.7e-65, 62.23% id in 286 aa, and to Rhizobium loti probable oxidoreductase mlr0254 SWALL:Q98N82 (EMBL:AP002994) (305 aa) fasta scores: E(): 8.4e-70, 65.3% id in 294 aa.
  
 
  0.845
hpcD
Similar to Escherichia coli 5-carboxymethyl-2-hydroxymuconate delta-isomerase HpcD SWALL:HPCD_ECOLI (SWALL:Q05354) (125 aa) fasta scores: E(): 2e-18, 48.41% id in 126 aa, and to Ralstonia solanacearum putative 5-carboxymethyl-2-hydroxymuconate delta-isomerase protein rsc2419 or rs02694 SWALL:Q8XWQ4 (EMBL:AL646070) (134 aa) fasta scores: E(): 2.6e-24, 50.79% id in 126 aa.
 
  
 0.813
hyi
Similar to Escherichia coli hydroxypyruvate isomerase Hyi or Gip or b0508 SWALL:HYI_ECOLI (SWALL:P30147) (258 aa) fasta scores: E(): 1.5e-54, 56.29% id in 254 aa, and to Ralstonia solanacearum probable hydroxypyruvate isomerase protein rsc3282 or rs02511 SWALL:Q8XUA9 (EMBL:AL646074) (260 aa) fasta scores: E(): 1.6e-69, 66.66% id in 261 aa; Belongs to the hyi family.
     
 0.801
gcl
Glyoxylate carboligase; Similar to Escherichia coli, and Escherichia coli O157:H7 glyoxylate carboligase Gcl or b0507 or z0661 or ecs0568 SWALL:GCL_ECOLI (SWALL:P30146) (592 aa) fasta scores: E(): 2.6e-187, 78.94% id in 589 aa, and to Pseudomonas aeruginosa glyoxylate carboligase pa1502 SWALL:Q9I3L0 (EMBL:AE004579) (591 aa) fasta scores: E(): 5.3e-192, 79.69% id in 591 aa; Belongs to the TPP enzyme family.
     
  0.800
BPSL0181
Putative exported protein; Similar to Ralstonia solanacearum putative signal peptide protein rsc0024 or rs01846 SWALL:Q8Y3F6 (EMBL:AL646057) (252 aa) fasta scores: E(): 2e-31, 43.7% id in 254 aa. C-terminus is similar to the C-terminal region of Neisseria meningitidis hypothetical protein NMB0419 SWALL:Q9K0Y5 (EMBL:AE002398) (198 aa) fasta scores: E(): 2.2e-11, 36.18% id in 152 aa.
       0.793
hpcB
Similar to Escherichia coli 3,4-dihydroxyphenylacetate 2,3-dioxygenase HpcB SWALL:HPCB_ECOLI (SWALL:Q05353) (275 aa) fasta scores: E(): 7e-71, 64.09% id in 259 aa, and to Salmonella typhi 3,4-dihydroxyphenylacetate 2,3-dioxygenase sty1137 SWALL:Q8Z7Q1 (EMBL:AL627269) (283 aa) fasta scores: E(): 6.1e-81, 66.31% id in 282 aa.
 
  
 0.789
BPSS0165
Putative dioxygenase; Similar to Salmonella typhi 3,4-dihydroxyphenylacetate 2,3-dioxygenase sty1137 SWALL:Q8Z7Q1 (EMBL:AL627269) (283 aa) fasta scores: E(): 6.7e-18, 29.21% id in 291 aa, and to Escherichia coli 3,4-dihydroxyphenylacetate 2,3-dioxygenase HpcB SWALL:HPCB_ECOLI (SWALL:Q05353) (275 aa) fasta scores: E(): 4.2e-16, 28.95% id in 259 aa.
 
  
 0.655
BPSS1093
Putative hydratase protein; Similar to Escherichia coli 2-keto-4-pentenoate hydratase MhpD or b0350 from codon 25 SWALL:MHPD_ECOLI (SWALL:P77608) (269 aa) fasta scores: E(): 5.1e-06, 30.07% id in 266 aa, and to Agrobacterium tumefaciens hypothetical protein atu4592 atu4592 or agr_l_566 from codon 24 SWALL:Q8U762 (EMBL:AE009387) (270 aa) fasta scores: E(): 2.2e-13, 29.54% id in 264 aa, and to Ralstonia solanacearum putative hydratase protein rsp0891 or rs01662 from codon 89 SWALL:Q8XRG3 (EMBL:AL646081) (265 aa) fasta scores: E(): 5e-07, 34.16% id in 161 aa. Possible alternative translat [...]
 
  
 0.651
BPSS0691
MarR family regulator protein; Similar to Escherichia coli, and Shigella flexneri homoprotocatechuate degradative operon repressor HpcR or HpaR SWALL:HPCR_ECOLI (SWALL:Q07095) (148 aa) fasta scores: E(): 6.2e-20, 46.04% id in 139 aa, and to Ralstonia solanacearum probable transcription regulator protein rsc1592 or rs03954 SWALL:Q8XZ14 (EMBL:AL646065) (154 aa) fasta scores: E(): 5.6e-21, 47.18% id in 142 aa.
 
   
 0.474
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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