STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSL0196Similar to Ralstonia solanacearum hypothetical protein rsc0026 or rs01849 SWALL:Q8Y3F4 (EMBL:AL646057) (215 aa) fasta scores: E(): 1.1e-59, 75.25% id in 194 aa, and to Neisseria meningitidis hypothetical protein NMB0939 SWALL:Q9JZQ6 (EMBL:AE002445) (193 aa) fasta scores: E(): 9.1e-32, 46.87% id in 192 aa. (204 aa)    
Predicted Functional Partners:
metXS
Putative homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
  
 0.998
BPSL0195
Putative membrane protein; Similar to Neisseria meningitidis AmpG-related protein NMB0360 SWALL:Q9K133 (EMBL:AE002392) (427 aa) fasta scores: E(): 4.9e-90, 54.76% id in 420 aa, and to Neisseria gonorrhoeae glutamine synthetase SWALL:P95363 (EMBL:U82701) (427 aa) fasta scores: E(): 4.2e-88, 53.57% id in 420 aa. Possible alternative translational start site.
       0.782
thrB
Homoserine kinase; Similar to Methylobacillus flagellatum homoserine kinase ThrB SWALL:KHSE_METFL (SWALL:Q9RAM6) (319 aa) fasta scores: E(): 2e-31, 44.2% id in 319 aa, and to Pseudomonas aeruginosa homoserine kinase pa5495 SWALL:KHSE_PSEAE (SWALL:P29364) (316 aa) fasta scores: E(): 6.4e-25, 43.08% id in 318 aa; Belongs to the pseudomonas-type ThrB family.
  
     0.616
BPSL0194
Conserved hypothetical protein; Similar to Ralstonia solanacearum hypothetical signal peptide protein rsc0153 or rs01023 SWALL:Q8Y328 (EMBL:AL646057) (314 aa) fasta scores: E(): 1e-30, 38.64% id in 295 aa. C-terminal region is similar to Pasteurella multocida hypothetical protein PM1190 SWALL:Q9CLN0 (EMBL:AE006159) (257 aa) fasta scores: E(): 4.5e-17, 29.21% id in 243 aa.
       0.577
BPSL2229
Similar to Pseudomonas putida siderophore non-ribosomal peptide synthetase PpsD SWALL:Q9AKS6 (EMBL:AJ310530) (2246 aa) fasta scores: E(): 4.8e-102, 28.54% id in 2659 aa, and to the C-terminal region of Pseudomonas syringae syringomycin synthetase SyrE SWALL:O85168 (EMBL:AF047828) (9376 aa) fasta scores: E(): 1.5e-94, 27.02% id in 3648 aa.
     
 0.498
BPSS1269
Putative peptide synthase/polyketide synthase; Similar to C-terminus of Aphanizomenon ovalisporum peptide synthetase AoaB SWALL:AAM33468 (EMBL:AF395828) (1869 aa) fasta scores: E(): 5.4e-125, 35.68% id in 1841 aa, and to C-terminus of Stigmatella aurantiaca MtaD SWALL:Q9RFK8 (EMBL:AF188287) (3291 aa) fasta scores: E(): 7.3e-124, 29.54% id in 3368 aa.
     
 0.498
argB
Putative acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
     
 0.462
BPSL1712
Putative non-ribosomal antibiotic-related peptide synthase; Similar to Pseudomonas syringae syringomycin synthetase SyrE SWALL:O85168 (EMBL:AF047828) (9376 aa) fasta scores: E(): 1.5e-105, 31.93% id in 6198 aa, and to all the domains of Bacillus brevis tyrocidine synthetase III TycC SWALL:TYCC_BACBR (SWALL:O30409) blast scores: E(): 0.0, score: 4799 27% id. Note: Taking into consideration the blastp similarities and all the similarities to the domains in Bacillus brevis TycC, it could be proposed that BSPL1712 possibly incorporates six amino acids (Asn, Gln, Tyr, Val, Orn and Leu) into [...]
     
 0.451
BPSS1008
Putative polyketide synthase; N-terminal region is similar to the the N-terminal region of Bacillus subtilis putative polyketide synthase PksK SWALL:PKSK_BACSU (SWALL:P40803) (4447 aa) fasta scores: E(): 1.1e-167, 38.79% id in 3439 aa. Internal region is similar to an internal region of Pseudomonas fluorescens MmpIV protein SWALL:Q8RL72 (EMBL:AF318063) (6521 aa) fasta scores: E(): 2.8e-41, 32.83% id in 4069 aa.
   
 
 0.445
SlmA
TetR family transcription regulatory protein; Similar to Ralstonia solanacearum probable transcription regulator protein rsc0031 or rs01854 SWALL:Q8Y3E9 (EMBL:AL646057) (218 aa) fasta scores: E(): 1.1e-34, 62.27% id in 220 aa, and to Vibrio cholerae TetR family transcriptional regulator VC0214 SWALL:Q9KVD2 (EMBL:AE004111) (210 aa) fasta scores: E(): 3.1e-20, 39.9% id in 218 aa.
   
   0.439
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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