STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSL0308Putative exported protein; N-terminal region is similar to Salmonella typhimurium putative membrane fusion protein SilB precursor silB SWALL:SILB_SALTY (SWALL:Q9ZHD0) (430 aa) fasta scores: E(): 1.8e-37, 31.41% id in 417 aa. Full length CDS is similar to Ralstonia solanacearum putative cation efflux system transmembrane protein rsp0927 or rs05406 SWALL:Q8XRD1 (EMBL:AL646081) (513 aa) fasta scores: E(): 3.2e-51, 38.89% id in 527 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (523 aa)    
Predicted Functional Partners:
silA
Similar to Salmonella typhimurium putative cation efflux system protein SilA SWALL:SILA_SALTY (SWALL:Q9ZHC9) (1048 aa) fasta scores: E(): 0, 61.03% id in 1047 aa, and to Ralstonia solanacearum probable cation efflux system transmembrane protein rsp0928 or rs05405 SWALL:Q8XRD0 (EMBL:AL646081) (1047 aa) fasta scores: E(): 0, 72.76% id in 1039 aa; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.991
BPSL0307
Outer membrane efflux protein; Similar to Alcaligenes eutrophus nickel and cobalt resistance protein CnrC SWALL:CNRC_ALCEU (SWALL:P37974) (418 aa) fasta scores: E(): 1.2e-10, 27.8% id in 410 aa, and to Ralstonia solanacearum putative outer membrane cation efflux protein rsp0926 or rs05407 SWALL:Q8XRD2 (EMBL:AL646081) (434 aa) fasta scores: E(): 2.4e-35, 35.96% id in 431 aa.
 
 
 0.975
czcA
Similar to Alcaligenes sp. cation efflux system protein CzcA SWALL:CZCA_ALCSP (SWALL:P94177) (1063 aa) fasta scores: E(): 0, 73.37% id in 1044 aa, and to Alcaligenes eutrophus cobalt-zinc-cadmium resistance protein CzcA SWALL:CZCA_ALCEU (SWALL:P13511) (1063 aa) fasta scores: E(): 0, 73.08% id in 1044 aa, and to Ralstonia solanacearum probable cation efflux system transmembrane protein CzcA or rsp0493 or rs00371 SWALL:Q8XSI1 (EMBL:AL646079) (1064 aa) fasta scores: E(): 0, 72.42% id in 1059 aa, and to Pseudomonas fluorescens CztA SWALL:Q9ALR2 (EMBL:AY007258) (1051 aa) fasta scores: E(): [...]
 
 0.947
macB
Macrolide-specific ABC-type efflux carrier; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.939
BPSL0310
Putative exported protein; Similar to Ralstonia solanacearum hypothetical signal peptide protein rsp0929 or rs05404 SWALL:Q8XRC9 (EMBL:AL646081) (114 aa) fasta scores: E(): 1.2e-07, 44.24% id in 113 aa. C-terminus is similar to the C-terminal region of Rhizobium meliloti hypothetical signal peptide protein smc02284 r00588 or smc02284 SWALL:Q92S41 (EMBL:AL591784) (94 aa) fasta scores: E(): 0.006, 36.98% id in 73 aa.
 
 
 0.867
czcC
Similar to Alcaligenes eutrophus cobalt-zinc-cadmium resistance protein CzcC precursor SWALL:CZCC_ALCEU (SWALL:P13509) (417 aa) fasta scores: E(): 4.7e-34, 39.75% id in 415 aa, and to Alcaligenes sp CzcC SWALL:P94175 (EMBL:D67044) (417 aa) fasta scores: E(): 1.5e-37, 41.3% id in 414 aa, and to Ralstonia solanacearum probable cobalt-zinc-cadmium outer membrane resistance protein CzcC or rsp0491 or rs00369 SWALL:Q8XSI3 (EMBL:AL646079) (441 aa) fasta scores: E(): 4.3e-36, 42.92% id in 424 aa.
 
 
 0.723
BPSL3094
Putative outer membrane bacteriocin efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
 
 
 0.628
BPSS0455
Putative copper resistance-related lipoprotein; Similar to Agrobacterium tumefaciens copper tolerance protein CopB or atu3992 or agr_l_1720 WALL:Q8U8U6 (EMBL:AE009330) (492 aa) fasta scores: E(): 1.1e-42, 40.04% id in 482 aa, and to Rhizobium meliloti hypothetical protein ra0562 or sma1037 SWALL:Q92ZC8 (EMBL:AE007246) (488 aa) fasta scores: E(): 3.4e-42, 39.17% id in 485 aa.
 
 
 0.621
BPSL0019
Outer membrane efflux lipoprotein; Previously sequenced as Burkholderia pseudomallei hypothetical 56.3 kDa protein SWALL:Q9ZF74 (EMBL:AF110185) (541 aa) fasta scores: E(): 5e-157, 98% id in 551 aa. CDS contains extra internal amino acid residues (514 to 524) relative to the previously sequenced protein. Similar to Pseudomonas aeruginosa outer membrane protein precursor OprM or OprK SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 3.8e-33, 34.73% id in 501 aa.
  
 
 0.551
oprB
Similar to Pseudomonas aeruginosa outer membrane protein OprM precursor pa0427 SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 4.1e-85, 55.67% id in 476 aa, and to Xanthomonas axonopodis outer membrane protein xac2842 SWALL:AAM37687 (EMBL:AE011925) (503 aa) fasta scores: E(): 5.8e-84, 53.72% id in 497 aa.
  
 
 0.551
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.