STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (249 aa)    
Predicted Functional Partners:
pgk
Similar to Escherichia coli phosphoglycerate kinase Pgk or b2926 SWALL:PGK_ECOLI (SWALL:P11665) (386 aa) fasta scores: E(): 1.8e-80, 63.7% id in 394 aa, and to Ralstonia solanacearum phosphoglycerate kinase Pgk or rsc0571 or rs04894 SWALL:Q8Y1W6 (EMBL:AL646060) (419 aa) fasta scores: E(): 1.7e-115, 85.64% id in 397 aa.
   
 0.987
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.983
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.978
BPSL2902
Putative phosphoglycerate mutase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri probable phosphoglycerate mutase GpmB or b4395 or z5997 or ecs5353 or sf4427 SWALL:GPMB_ECOLI (SWALL:P36942) (215 aa) fasta scores: E(): 1.7e-12, 36.19% id in 221 aa, and to Ralstonia solanacearum putative phosphoglycerate mutase 2 protein rsc0499 or rs05023 SWALL:Q8Y237 (EMBL:AL646059) (227 aa) fasta scores: E(): 1.8e-33, 46.84% id in 222 aa.
  
 
0.940
cbbA
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
   
 
 0.939
pgi
Glucose-6-phosphate isomerase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucose-6-phosphate isomerase Pgi or b4025 or z5623 or ecs5008 SWALL:G6PI_ECOLI (SWALL:P11537) (549 aa) fasta scores: E(): 2.5e-100, 49.9% id in 543 aa, and to Deinococcus radiodurans glucose-6-phosphate isomerase dr1742 SWALL:G6PI_DEIRA (SWALL:Q9RTL8) (541 aa) fasta scores: E(): 7.5e-120, 57.22% id in 540 aa.
   
 
 0.939
BPSL0116
D-isomer specific 2-hydroxyacid dehydrogenase; Similar to Escherichia coli 2-ketogluconate reductase TkrA SWALL:TKRA_ECOLI (SWALL:P37666) (324 aa) fasta scores: E(): 8.3e-17, 28% id in 325 aa, and to Ralstonia solanacearum putative D-3-phosphoglycerate dehydrogenase oxidoreductase protein rsc0016 or rs01838 SWALL:Q8Y3G4 (EMBL:AL646057) (353 aa) fasta scores: E(): 8.8e-100, 72.72% id in 341 aa; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 0.914
serA
D-3-phosphoglycerate dehydrogenase; Similar to Escherichia coli, and Escherichia coli O157:H7 D-3-phosphoglycerate dehydrogenase SerA or b2913 or z4251 or ecs3784 SWALL:SERA_ECOLI (SWALL:P08328) (409 aa) fasta scores: E(): 3.4e-73, 54.52% id in 398 aa, and to Bordetella pertussis D-3-phosphoglycerate dehydrogenase homolog SerA SWALL:O30440 (EMBL:AF006000) (399 aa) fasta scores: E(): 9.7e-79, 57.14% id in 399 aa; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 0.914
talB
Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 0.912
BPSL1401
Putative kinase; Similar to Pseudomonas aeruginosa hypothetical protein pa1052 SWALL:Q9I4S2 (EMBL:AE004537) (381 aa) fasta scores: E(): 5.2e-50, 50.13% id in 377 aa, and to Bacillus subtilis glycerate kinase GlxK or S14A SWALL:GRK_BACSU (SWALL:P42100) (382 aa) fasta scores: E(): 1.1e-38, 40.1% id in 379 aa.
     
 0.905
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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