STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
kdpAPotassium-transporting ATPase a chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (602 aa)    
Predicted Functional Partners:
kdpB
Potassium-transporting ATPase b chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
 
 0.999
kdpC
Potassium-transporting ATPase c chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 
 0.999
kdpD
Similar to Escherichia coli sensor protein KdpD or b0695 SWALL:KDPD_ECOLI (SWALL:P21865) (894 aa) fasta scores: E(): 8.8e-93, 49.39% id in 913 aa, and to Salmonella typhi sensor protein sty0744 SWALL:Q8Z8E7 (EMBL:AL627267) (902 aa) fasta scores: E(): 3.5e-97, 48.91% id in 924 aa. Note: This CDS is longer in its C-terminal region than most of its database matches.
 
  
 0.970
kdpE
Similar to Escherichia coli kdp operon transcriptional regulatory protein KdpE or b0694 SWALL:KDPE_ECOLI (SWALL:P21866) (225 aa) fasta scores: E(): 3.6e-56, 65.31% id in 222 aa, and to Salmonella typhimurium response regulator in two-component regulatory system with KdpD, regulates kdp operon encoding a high-affinity K translocating ATPase stm0702 SWALL:Q8ZQW5 (EMBL:AE008728) (225 aa) fasta scores: E(): 2.8e-55, 63.51% id in 222 aa.
 
  
 0.892
BPSL1170
Putative membrane protein; Similar to Xanthomonas campestris pv. campestris str. ATCC 33913 conserved hypothetical protein xcc0701 SWALL:AAM40017 (EMBL:AE012169) (30 aa) fasta scores: E(): 0.11, 44.44% id in 27 aa, and to Escherichia coli protein KdpF or b0698.1 SWALL:KDPF_ECOLI (SWALL:P36937) (29 aa) fasta scores: E(): 4.4, 73.33% id in 15 aa.
       0.793
kup
Kup system potassium uptake protein; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.
   
  
 0.651
mscL
Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
      
 0.543
BPSL0539
Sodium/hydrogen exchanger family protein; N-terminal region is similar to Escherichia coli glutathione-regulated potassium-efflux system protein KefB or TrkB SWALL:KEFB_ECOLI (SWALL:P45522) (601 aa) fasta scores: E(): 4.3e-51, 33.63% id in 562 aa. Full length CDS is similar to Ralstonia solanacearum putative glutathione-regulated potassium-efflux system K+/H+ antiporter transmembrane protein rsc0414 or rs03382 SWALL:Q8Y2C2 (EMBL:AL646059) (659 aa) fasta scores: E(): 2.6e-158, 66.86% id in 658 aa; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.404
sbp
Similar to Salmonella typhimurium sulfate-binding protein precursor Sbp SWALL:SUBI_SALTY (SWALL:P02906) (329 aa) fasta scores: E(): 3.4e-65, 55.52% id in 326 aa, and to Ralstonia solanacearum probable sulfate-binding precursor signal peptide protein rsc1336 or rs02858 SWALL:Q8XZQ9 (EMBL:AL646064) (336 aa) fasta scores: E(): 1.3e-68, 59.13% id in 323 aa. BPSL1839, 58.480% identity (60.606% ungapped) in 342 aa overlap.
      
 0.403
cysA
Sulfate transport ATP-binding protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.
     
 0.403
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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