STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSL1486Hypothetical protein; Only central part similar to Ralstonia solanacearum putative COMEA-related signal peptide protein rsc0916 or rs04499 SWALL:Q8Y0X7 (EMBL:AL646061) (105 aa) fasta scores: E(): 1.5e-06, 51.92% id in 104 aa. Note: C-terminal region presents two regions of high hidrophilicity, high content in alanine amino acid residues, high G+C content and no databsse matches. (231 aa)    
Predicted Functional Partners:
BPSL2274
Putative membrane protein; C-terminal region is similar to Neisseria gonorrhoeae competence protein ComA SWALL:COMA_NEIGO (SWALL:P51973) (691 aa) fasta scores: E(): 3.6e-18, 35.73% id in 778 aa> Full length CDS is similar to Xanthomonas campestris DNA uptake/competence protein xcc2123 SWALL:AAM41408 (EMBL:AE012319) (796 aa) fasta scores: E(): 7.5e-29, 38.66% id in 869 aa.
 
  
 0.696
BPSL1485
Similar to Escherichia coli hypothetical protein YidB or b3698 SWALL:YIDB_ECOLI (SWALL:P09996) (132 aa) fasta scores: E(): 1.1e-09, 37.39% id in 115 aa, and to Rhizobium loti hypothetical protein mlr4715 SWALL:Q98DG3 (EMBL:AP003004) (165 aa) fasta scores: E(): 1.9e-08, 33.85% id in 127 aa.
       0.560
BPSL1898
Family A24A unassigned peptidase; Similar to the plasmid borne Ralstonia solanacearum probable prepilin peptidase transmembrane protein CpaA2 or rsp1091 or rs02612 SWALL:Q8XQX7 (EMBL:AL646082) (168 aa) fasta scores: E(): 8.9e-11, 38.88% id in 162 aa, and to the C-terminal region of Escherichia coli type 4 prepilin-like proteins leader peptide processing enzyme [includes: leader peptidase (EC 3.4.99.-) (prepilin peptidase); n-methyltransferase (EC 2.1.1.-)] HofD or HopD or HopO or b3335 SWALL:LEP4_ECOLI (SWALL:P25960) (225 aa) fasta scores: E(): 0.0086, 25.67% id in 148 aa.
   
  
 0.527
gspO
Type IV prepilin leader peptide type M1; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
   
  
 0.527
queF
Putative GTP cyclohydrolase I; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
     
 0.502
gspF
General secretory pathway protein F; Previously sequenced as Burkholderia pseudomallei general secretory pathway protein F GspF SWALL:Q9ZF84 (EMBL:AF110185) (405 aa) fasta scores: E(): 2.3e-145, 99.25% id in 405 aa. Similar to Erwinia carotovora general secretion pathway protein F OutF SWALL:GSPF_ERWCA (SWALL:P31705) (408 aa) fasta scores: E(): 9.6e-60, 43.1% id in 406 aa.
  
  
 0.483
pilC
Similar to Burkholderia pseudomallei pilus assembly protein PilC SWALL:Q9ZF71 (EMBL:AF110186) (186 aa) fasta scores: E(): 6e-62, 98.92% id in 186 aa, and to Aeromonas hydrophila type IV pilus assembly protein TapC SWALL:TAPC_AERHY (SWALL:P45793) (413 aa) fasta scores: E(): 1e-44, 35.85% id in 396 aa.
  
  
 0.483
pilR
Putative type IV pilus biosynthesis protein; Similar to Escherichia coli BfpE SWALL:Q47071 (EMBL:Z68186) (352 aa) fasta scores: E(): 3e-47, 38.06% id in 352 aa, and to Salmonella typhi, and Salmonella dublin PilR or sty4546 SWALL:Q9ZIV0 (EMBL:AF000001) (361 aa) fasta scores: E(): 9.3e-29, 34.07% id in 361 aa.
  
  
 0.483
ssb
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
  
 0.472
BPSL1487
Similar to Clostridium acetobutylicum transcriptional regulator, MerR family cac3507 SWALL:Q97DH0 (EMBL:AE007847) (126 aa) fasta scores: E(): 8.7e-14, 41.96% id in 112 aa, and to Streptomyces coelicolor putative MerR-family transcriptional regulator sco2875 or sce6.12 SWALL:Q9KZS6 (EMBL:AL353832) (135 aa) fasta scores: E(): 2.3e-11, 41.88% id in 117 aa. Note: this CDS is longer in its C-terminal region than most of its database matches.
       0.449
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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