STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gabDSimilar to Escherichia coli succinate-semialdehyde dehydrogenase [NADP+] GabD or b2661 SWALL:GABD_ECOLI (SWALL:P25526) (482 aa) fasta scores: E(): 2e-126, 66.45% id in 480 aa, and to Pseudomonas aeruginosa succinate-semialdehyde dehydrogenase pa0265 SWALL:Q9I6M5 (EMBL:AE004464) (483 aa) fasta scores: E(): 1e-130, 69.03% id in 478 aa. (486 aa)    
Predicted Functional Partners:
BPSL2002
Putative iron-containing alcohol dehydrogenase; Similar to Citrobacter freundii 1,3-propanediol dehydrogenase DhaT SWALL:DHAT_CITFR (SWALL:P45513) (387 aa) fasta scores: E(): 5.4e-34, 36.79% id in 375 aa, to Bacillus subtilis alcohol dehydrogenase GbsB SWALL:GBSB_BACSU (SWALL:P71017) (402 aa) fasta scores: E(): 1e-28, 33.42% id in 371 aa, and to Ralstonia solanacearum probable NAD-dependent 4-hydroxybutyrate dehydrogenase oxidoreductase protein rsc1771 or rs02958 SWALL:Q8XYI7 (EMBL:AL646066) (382 aa) fasta scores: E(): 5.7e-117, 80.89% id in 382 aa.
 
 0.922
gabT
Similar to Escherichia coli 4-aminobutyrate aminotransferase GabT or b2662 SWALL:GABT_ECOLI (SWALL:P22256) (426 aa) fasta scores: E(): 4.8e-79, 54.24% id in 424 aa, and to Ralstonia solanacearum probable 4-aminobutyrate aminotransferase protein rsc0029 or rs01852 SWALL:Q8Y3F1 (EMBL:AL646057) (426 aa) fasta scores: E(): 1.5e-108, 71.29% id in 418 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.922
sdhA
Succinate dehydrogenase flavoprotein subunit; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 succinate dehydrogenase flavoprotein subunit SdhA or b0723 or c0801 or z0877 or ecs0748 SWALL:DHSA_ECOLI (SWALL:P10444) (588 aa) fasta scores: E(): 7.9e-127, 55.46% id in 586 aa, and to Ralstonia solanacearum putative succinate dehydrogenase SdhA or rsc1994 or rs03562 SWALL:Q8XXW9 (EMBL:AL646067) (592 aa) fasta scores: E(): 6.1e-201, 85.3% id in 592 aa; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
   
 0.921
sdhB
Similar to Escherichia coli succinate dehydrogenase iron-sulfur protein SdhB or b0724 SWALL:DHSB_ECOLI (SWALL:P07014) (238 aa) fasta scores: E(): 5.9e-65, 66.81% id in 232 aa, and to Ralstonia solanacearum putative succinate dehydrogenase rsc1993 or rs03561 SWALL:Q8XXX0 (EMBL:AL646067) (233 aa) fasta scores: E(): 5.5e-89, 90.51% id in 232 aa; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
   
 
 0.908
sdhB-2
Similar to Escherichia coli succinate dehydrogenase iron-sulfur protein SdhB SWALL:DHSB_ECOLI (SWALL:P07014) (238 aa) fasta scores: E(): 3.3e-63, 63.79% id in 232 aa, and to Ralstonia solanacearum putative succinate dehydrogenase rsc1993 or rs03561 SWALL:Q8XXX0 (EMBL:AL646067) (233 aa) fasta scores: E(): 1.7e-74, 73.16% id in 231 aa. Similar to BPSS1717, 74.459% identity (74.783% ungapped) in 231 aa overlap.
   
 
 0.908
BPSS0514
acetyl-CoA hydrolase/transferase; Similar to Clostridium kluyveri succinyl-CoA:coenzyme A transferase Cat1 SWALL:CAT1_CLOKL (SWALL:P38946) (538 aa) fasta scores: E(): 2e-97, 51.73% id in 520 aa, and to Xanthomonas campestris coa tranferase xcc3588 SWALL:Q8P4W8 (EMBL:AE012479) (504 aa) fasta scores: E(): 1.2e-133, 68.52% id in 502 aa. Possible alternative translational start sites.
  
 
 0.903
hpcH
Similar to Escherichia coli 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase HpcH or HpaI SWALL:HPAI_ECOLI (SWALL:Q47098) (262 aa) fasta scores: E(): 9.1e-58, 67.3% id in 260 aa, and to Ralstonia solanacearum putative 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase oxidoreductase protein rsc1591 or rs03953 SWALL:Q8XZ15 (EMBL:AL646065) (272 aa) fasta scores: E(): 4.4e-61, 69.61% id in 260 aa; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.903
BPSS1719
Putative succinate dehydrogenase; Similar to Ralstonia solanacearum putative transmembrane succinate dehydrogenase sdhd or rsc1995 or rs03563 SWALL:Q8XXW8 (EMBL:AL646067) (121 aa) fasta scores: E(): 1.2e-35, 71.31% id in 122 aa, and to Escherichia coli, Escherichia coli O6, and Shigella flexneri succinate dehydrogenase hydrophobic membrane anchor protein sdhd or b0722 or c0800 or sf0575 SWALL:DHSD_ECOLI (SWALL:P10445) (115 aa) fasta scores: E(): 1.7e-10, 32.69% id in 104 aa.
   
 
 0.903
BPSS1720
Similar to Ralstonia solanacearum putative transmembrane succinate dehydrogenase SdhC or rsc1996 or rs03564 SWALL:Q8XXW7 (EMBL:AL646067) (140 aa) fasta scores: E(): 1.1e-30, 58.69% id in 138 aa, and to Escherichia coli, and Escherichia coli O157:H7 succinate dehydrogenase cytochrome b-556 subunit SdhC or CybA or b0721 or z0875 or ecs0746 SWALL:DHSC_ECOLI (SWALL:P10446) (129 aa) fasta scores: E(): 7.3e-11, 35.15% id in 128 aa.
   
 
  0.903
gabD-2
Similar to Escherichia coli succinate-semialdehyde dehydrogenase [NADP+] GabD or b2661 SWALL:GABD_ECOLI (SWALL:P25526) (482 aa) fasta scores: E(): 1.4e-130, 69.7% id in 482 aa, and to Salmonella typhi succinate-semialdehyde dehydrogenase sty2911 SWALL:Q8Z4F8 (EMBL:AL627276) (482 aa) fasta scores: E(): 7.2e-131, 70.12% id in 482 aa.
  
  
 
0.900
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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