STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSL1676Similar to Rhizobium meliloti putative histidine ammonia-lyase ra0165 or sma0306 SWALL:Q930N0 (EMBL:AE007210) (546 aa) fasta scores: E(): 1.8e-108, 55.01% id in 538 aa, and to Rhizobium loti histidine ammonia-lyase mll7124 SWALL:Q987B4 (EMBL:AP003011) (498 aa) fasta scores: E(): 2.8e-21, 32.15% id in 510 aa. Note: Similar also to many eukaryotic proteins. (544 aa)    
Predicted Functional Partners:
hutU-2
Putative urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.996
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.992
hutI
Similar to Bacillus subtilis imidazolonepropionase HutI SWALL:HUTI_BACSU (SWALL:P42084) (421 aa) fasta scores: E(): 2.6e-48, 38.96% id in 385 aa, and to Pseudomonas aeruginosa imidazolonepropionase pa5092 SWALL:HUTI_PSEAE (SWALL:Q9HU91) (402 aa) fasta scores: E(): 4.7e-87, 59.7% id in 402 aa; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
  
 0.964
hutH
Similar to Pseudomonas putida histidine ammonia-lyase HutH SWALL:HUTH_PSEPU (SWALL:P21310) (509 aa) fasta scores: E(): 5.6e-112, 63.4% id in 500 aa, and to Vibrio cholerae histidine ammonia-lyase vc1202 SWALL:HUTH_VIBCH (SWALL:Q9KSQ4) (511 aa) fasta scores: E(): 3.7e-114, 64.38% id in 483 aa; Belongs to the PAL/histidase family.
  
  
 
0.926
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
    
 0.925
BPSL1677
Putative transport-related, integral membrane protein; Similar to Escherichia coli citrate-proton symporter CitA or Cit SWALL:CIT1_ECOLI (SWALL:P07661) (431 aa) fasta scores: E(): 1.9e-51, 36.72% id in 422 aa, and to Ralstonia solanacearum probable sugar-proton symporter transmembrane protein rsp0536 or rs00416 SWALL:Q8XSE0 (EMBL:AL646079) (441 aa) fasta scores: E(): 1.6e-63, 44.55% id in 404 aa.
       0.732
BPSL1679
Similar to Agrobacterium tumefaciens hypothetical protein atu3042 or agr_l_3523 SWALL:Q8UBH4 (EMBL:AE009235) (358 aa) fasta scores: E(): 6.2e-11, 25.13% id in 366 aa, and to Rhizobium loti hypothetical protein mll9130 SWALL:Q982D2 (EMBL:AP003015) (361 aa) fasta scores: E(): 4.6e-10, 26.03% id in 338 aa.
 
   
 0.618
BPSL0500
Putative chitobiase; Similar to Serratia marcescens chitobiase precursor Chb SWALL:CHB_SERMA (SWALL:Q54468) (885 aa) fasta scores: E(): 2e-118, 46.94% id in 801 aa, and to Burkholderia cepacia putative chitinase Bcc1 SWALL:Q9F1K5 (EMBL:AB053088) (826 aa) fasta scores: E(): 0, 85.8% id in 831 aa. CDS is truncated at the C-terminus in comparison to orthologues.
   
    0.603
speB
Agmatinase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri agmatinase SpeB or b2937 or z4281 or ecs3812 or sf2927 SWALL:SPEB_ECOLI (SWALL:P16936) (306 aa) fasta scores: E(): 3e-50, 48.03% id in 306 aa, and to Rhizobium loti agmatinase mll8453 SWALL:Q982X2 (EMBL:AP003014) (335 aa) fasta scores: E(): 1.9e-57, 52.42% id in 309 aa; Belongs to the arginase family.
  
  
 0.565
speB-2
Agmatinase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri agmatinase SpeB or b2937 or z4281 or ecs3812 or sf2927 SWALL:SPEB_ECOLI (SWALL:P16936) (306 aa) fasta scores: E(): 1.3e-23, 42.17% id in 294 aa, and to Pseudomonas aeruginosa agmatinase SpeB2 or pa1421 SWALL:Q9I3S3 (EMBL:AE004571) (319 aa) fasta scores: E(): 1.3e-89, 71.47% id in 319 aa; Belongs to the arginase family.
  
  
 0.565
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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