STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
amrBMultidrug efflux system transporter protein AmrB; Almost identical to previously sequenced Burkholderia pseudomallei putative transporter AmrB SWALL:O87936 (EMBL:AF072887) (1043 aa) fasta scores: E(): 0, 99.8% id in 1043 aa. Similar to Escherichia coli acriflavine resistance protein B AcrB or AcrE or b0462 SWALL:ACRB_ECOLI (SWALL:P31224) (1049 aa) fasta scores: E(): 5.5e-199, 51.79% id in 1033 aa. (1043 aa)    
Predicted Functional Partners:
amrA
Almost identical to Burkholderia pseudomallei putative membrane fusion protein AmrA SWALL:O87935 (EMBL:AF072887) (399 aa) fasta scores: E(): 7.7e-133, 99.74% id in 399 aa. Similar to Escherichia coli, and Escherichia coli O157:H7 acriflavine resistance protein A precursor AcrA or MtcA or Lir or b0463 or z0578 or ecs0516 SWALL:ACRA_ECO57 (SWALL:P31223) (397 aa) fasta scores: E(): 3.5e-43, 40.1% id in 384 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 0.998
BPSL1802
Multidrug efflux system putative membrane lipoprotein; Similar to Pseudomonas aeruginosa outer membrane protein precursor OprM or OprK or pa0427 SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 2.3e-59, 46.39% id in 485 aa, and to Xanthomonas axonopodis outer membrane protein OprM or xac2842 SWALL:AAM37687 (EMBL:AE011925) (503 aa) fasta scores: E(): 9.5e-65, 47.54% id in 488 aa.
 0.990
bpeA
Similar to Escherichia coli, and Escherichia coli O157:H7 acriflavine resistance protein A precursor acrA or MtcA or Lir SWALL:ACRA_ECOLI (SWALL:P31223) (397 aa) fasta scores: E(): 5.5e-60, 53.76% id in 385 aa, and to Ralstonia solanacearum probable acriflavin resistance lipoprotein A precursor rsc0011 or rs01833 SWALL:Q8Y3G9 (EMBL:AL646057) (398 aa) fasta scores: E(): 6.6e-61, 55.22% id in 402 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 0.987
oprB
Similar to Pseudomonas aeruginosa outer membrane protein OprM precursor pa0427 SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 4.1e-85, 55.67% id in 476 aa, and to Xanthomonas axonopodis outer membrane protein xac2842 SWALL:AAM37687 (EMBL:AE011925) (503 aa) fasta scores: E(): 5.8e-84, 53.72% id in 497 aa.
 0.984
BPSS1120
Putative outer membrane efflux protein; Similar to Pseudomonas putida efflux protein TtgC SWALL:Q9WWZ8 (EMBL:AF031417) (484 aa) fasta scores: E(): 9.1e-76, 49.68% id in 483 aa, and to Pseudomonas aeruginosa outer membrane protein OprM precursor or OprK or pa0427 SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 3.8e-85, 56.19% id in 468 aa, and to Xanthomonas axonopodis outer membrane protein OprM or xac2842 SWALL:AAM37687 (EMBL:AE011925) (503 aa) fasta scores: E(): 5.4e-84, 53.18% id in 502 aa.
 0.952
bpeB
Similar to Escherichia coli acriflavine resistance protein B AcrB or AcrE or b0462 SWALL:ACRB_ECOLI (SWALL:P31224) (1049 aa) fasta scores: E(): 0, 66.63% id in 1049 aa, and to Klebsiella pneumoniae AcrB protein SWALL:Q93K40 (EMBL:AJ318073) (1048 aa) fasta scores: E(): 0, 66.79% id in 1048 aa.
  
  
0.906
oprM
Similar to Pseudomonas aeruginosa outer membrane protein OprM or OprK SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 5.5e-60, 50.92% id in 487 aa, and to Xanthomonas campestris outer membrane protein xcc2681 SWALL:AAM41953 (EMBL:AE012380) (497 aa) fasta scores: E(): 7e-62, 51.91% id in 495 aa. CDS is extended at the C-terminus in comparison to orthologues. Probable gene fusion resulting from the loss of a stop codon. The effect on the function of CDS is not known.
 
 0.887
BPSL3094
Putative outer membrane bacteriocin efflux protein; CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
  
 0.845
BPSS1287
Putative outer membrane efflux protein; Similar to Enterobacter aerogenes TolC protein precursor SWALL:Q8VLQ0 (EMBL:AJ421426) (486 aa) fasta scores: E(): 1e-19, 26.16% id in 451 aa, and to Ralstonia solanacearum probable porin rsc0695 or rs01600 SWALL:Q8Y1J5 (EMBL:AL646060) (484 aa) fasta scores: E(): 4.3e-25, 27.8% id in 446 aa.
  
 0.845
BPSS0292
Putative multidrug efflux system exported protein; Similar to Escherichia coli, and Escherichia coli O157:H7 acriflavine resistance protein A precursor AcrA or MtcA or Lir or b0463 or z0578 or ecs0516 SWALL:ACRA_ECOLI (SWALL:P31223) (397 aa) fasta scores: E(): 5.3e-33, 32.98% id in 385 aa, and to Ralstonia solanacearum probable transmembrane multidrug efflux system transmembrane protein ys02620 or rsp1112 or rs02620 SWALL:Q8XQV6 (EMBL:AL646082) (438 aa) fasta scores: E(): 6.1e-78, 57.77% id in 405 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.832
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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