Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
BPSL1975Putative antibiotic resistance protein; Full length similar to Pseudomonas aeruginosa hypothetical protein pa3892 SWALL:Q9HXC1 (EMBL:AE004806) (302 aa) fasta scores: E(): 3.2e-74, 67.59% id in 287 aa, and to Escherichia coli multidrug resistance protein K EmrK or b2368 SWALL:EMRK_ECOLI (SWALL:P52599) (387 aa) fasta scores: E(): 4.6e-09, 28.35% id in 335 aa, and C-terminal region to Burkholderia cepacia fusaric acid resistance protein FusE SWALL:FUSE_BURCE (SWALL:P24130) (168 aa) fasta scores: E(): 7.1e-46, 81.65% id in 169 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (297 aa)    
Predicted Functional Partners:
BPSL1973
Putative antibiotic resistance protein; N-terminal region similar to Burkholderia cepacia fusaric acid resistance protein FusB SWALL:FUSB_BURCE (SWALL:P24127) (142 aa) fasta scores: E(): 5.2e-11, 71.23% id in 73 aa, central region to Burkholderia cepacia fusaric acid resistance protein FusC SWALL:FUSC_BURCE (SWALL:P24128) (346 aa) fasta scores: E(): 2.5e-99, 78.77% id in 344 aa, and C-terminal region to Burkholderia cepacia fusaric acid resistance protein FusD fusD SWALL:FUSD_BURCE (SWALL:P24129) (208 aa) fasta scores: E(): 7.6e-54, 75.59% id in 209 aa. Note: Seems to be a fusion of th [...]
 
  
 0.971
BPSL1974
Putative membrane protein; Similar to Brucella melitensis hypothetical membrane associated protein bmeii0532 SWALL:Q8YCJ6 (EMBL:AE009689) (69 aa) fasta scores: E(): 0.00012, 40.67% id in 59 aa, and to Salmonella typhimurium, and Salmonella typhi putative inner membrane protein YhcR or stm3366 or sty3546A SWALL:Q8XEK3 (EMBL:AE008855) (67 aa) fasta scores: E(): 0.0019, 30.76% id in 52 aa.
 
     0.909
BPSL1972
Putative antibiotic resistance membrane protein; Similar to Burkholderia cepacia fusaric acid resistance protein precursor FusA SWALL:FUSA_BURCE (SWALL:P24126) (530 aa) fasta scores: E(): 5.8e-82, 62.82% id in 538 aa, and to Pseudomonas aeruginosa outer membrane protein OprM precursor or OprK or pa0427 SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 1.2e-19, 28.84% id in 475 aa. Note: Contains a highly conserved repeat at the C-terminal region (from residue 496) that has no similarities to database entries.
 
 
 0.905
BPSS0754
Putative membrane protein; Similar to Pseudomonas aeruginosa hypothetical protein pa3893 SWALL:Q9HXC0 (EMBL:AE004806) (731 aa) fasta scores: E(): 1.2e-94, 41.24% id in 708 aa. C-terminal region is similar to Burkholderia cepacia fusaric acid resistance protein FusD SWALL:FUSD_BURCE (SWALL:P24129) (208 aa) fasta scores: E(): 2e-22, 43.5% id in 200 aa.
 
  
 0.825
macB
Macrolide-specific ABC-type efflux carrier; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.721
BPSL0019
Outer membrane efflux lipoprotein; Previously sequenced as Burkholderia pseudomallei hypothetical 56.3 kDa protein SWALL:Q9ZF74 (EMBL:AF110185) (541 aa) fasta scores: E(): 5e-157, 98% id in 551 aa. CDS contains extra internal amino acid residues (514 to 524) relative to the previously sequenced protein. Similar to Pseudomonas aeruginosa outer membrane protein precursor OprM or OprK SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 3.8e-33, 34.73% id in 501 aa.
 
 
 0.604
BPSL1913
Putative exported protein; Similar to Ralstonia solanacearum putative outer membrane chanel lipoprotein rsc1294 or rs02807 SWALL:Q8XZV1 (EMBL:AL646063) (489 aa) fasta scores: E(): 1.9e-77, 48.72% id in 470 aa, and to Xanthomonas axonopodis outer membrane efflux protein YjcP or xac1444 SWALL:AAM36315 (EMBL:AE011776) (496 aa) fasta scores: E(): 6.1e-56, 38.46% id in 481 aa.
 
 
 0.569
BPSL2234
Putative exported protein; Similar to Escherichia coli hypothetical protein precursor YegM or b2074 SWALL:YEGM_ECOLI (SWALL:P76397) (415 aa) fasta scores: E(): 2.5e-37, 36.29% id in 405 aa, and to Rhizobium loti RND efflux membrane fusion protein mll5780 SWALL:Q98B05 (EMBL:AP003007) (417 aa) fasta scores: E(): 1.5e-35, 34.54% id in 414 aa.
 
   
 0.561
oprB
Similar to Pseudomonas aeruginosa outer membrane protein OprM precursor pa0427 SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 4.1e-85, 55.67% id in 476 aa, and to Xanthomonas axonopodis outer membrane protein xac2842 SWALL:AAM37687 (EMBL:AE011925) (503 aa) fasta scores: E(): 5.8e-84, 53.72% id in 497 aa.
 
 
 0.555
BPSS1120
Putative outer membrane efflux protein; Similar to Pseudomonas putida efflux protein TtgC SWALL:Q9WWZ8 (EMBL:AF031417) (484 aa) fasta scores: E(): 9.1e-76, 49.68% id in 483 aa, and to Pseudomonas aeruginosa outer membrane protein OprM precursor or OprK or pa0427 SWALL:OPRM_PSEAE (SWALL:Q51487) (485 aa) fasta scores: E(): 3.8e-85, 56.19% id in 468 aa, and to Xanthomonas axonopodis outer membrane protein OprM or xac2842 SWALL:AAM37687 (EMBL:AE011925) (503 aa) fasta scores: E(): 5.4e-84, 53.18% id in 502 aa.
 
 
 0.553
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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