Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
glnSSimilar to Escherichia coli glutaminyl-tRNA synthetase GlnS or b0680 SWALL:SYQ_ECOLI (SWALL:P00962) (553 aa) fasta scores: E(): 9.9e-131, 57.34% id in 558 aa, and to Ralstonia solanacearum glutaminyl-tRNA synthetase rsc0791 or rs05046 SWALL:Q8Y199 (EMBL:AL646061) (580 aa) fasta scores: E(): 1.9e-175, 70.35% id in 570 aa. (569 aa)    
Predicted Functional Partners:
gatB
glutamyl-tRNA amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily.
  
 0.979
gatA
glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
  
 0.938
gatC
glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.
  
 
 0.932
lysS
lysyl-tRNA synthetase; Similar to Escherichia coli, and Escherichia coli O6 lysyl-tRNA synthetase LysS or HerC or AsuD SWALL:SYK1_ECOLI (SWALL:P13030) (504 aa) fasta scores: E(): 3.9e-116, 57.82% id in 505 aa, and to Ralstonia solanacearum putative lysyl-tRNA synthetase protein rsc1028 or rs04223 SWALL:Q8Y0L5 (EMBL:AL646062) (510 aa) fasta scores: E(): 2.3e-173, 81.96% id in 510 aa; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 0.931
BPSL2536
Putative amidotransferase; Similar to Streptomyces coelicolor glutamyl-tRNA GatA or sco5499 or sc8d9.11 SWALL:GATA_STRCO (SWALL:Q9Z580) (497 aa) fasta scores: E(): 3e-21, 33.6% id in 485 aa, Ralstonia solanacearum putative amidotransferase amidase protein rsc0589 or rs04871 SWALL:Q8Y1V0 (EMBL:AL646060) (448 aa) fasta scores: E(): 1.3e-77, 56.98% id in 451 aa, and to Brucella melitensis glutamyl-tRNA bmei1360 SWALL:Q8YG02 (EMBL:AE009574) (471 aa) fasta scores: E(): 6.3e-51, 44.97% id in 438 aa; Belongs to the amidase family.
  
 0.931
BPSS1659
Hypothetical protein; No significant database matches.
  
 0.931
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 0.928
rplW
50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
   
 0.924
rplR
50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
   
 0.921
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
 0.921
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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