STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dadXAlanine racemase, catabolic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (356 aa)    
Predicted Functional Partners:
ddlB
D-alanine--d-alanine ligase B; Cell wall formation.
 
 
 0.966
ald
Similar to Vibrio proteolyticus alanine dehydrogenase ald SWALL:O85596 (EMBL:AF070716) (374 aa) fasta scores: E(): 5.5e-77, 63.76% id in 367 aa, and to Vibrio cholerae alanine dehydrogenase vc1905 SWALL:Q9KQU3 (EMBL:AE004266) (374 aa) fasta scores: E(): 3.2e-77, 64.01% id in 364 aa; Belongs to the AlaDH/PNT family.
  
 
 0.949
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
   
 0.943
BPSL0409
Putative D-amino acid aminotransferase; Similar to Bacillus licheniformis D-alanine aminotransferase Dat SWALL:DAAA_BACLI (SWALL:P54692) (283 aa) fasta scores: E(): 8.7e-28, 40.42% id in 282 aa, and to Listeria innocua D-alanine aminotransferase lin1660 SWALL:DAAA_LISIN (SWALL:Q92B90) (289 aa) fasta scores: E(): 1.8e-27, 36.74% id in 283 aa.
    
 0.921
dadX-2
Alanine racemase, catabolic; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
  
0.902
radA
DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
 
    0.825
BPSL1476
Putative aminotransferase; Similar to Ralstonia solanacearum probable aspartate aminotransferase protein rsc1326 or rs02848 SWALL:Q8XZR9 (EMBL:AL646064) (413 aa) fasta scores: E(): 3.1e-130, 76.58% id in 410 aa, and to Escherichia coli probable aminotransferase YfbQ or b2290 SWALL:YFBQ_ECOLI (SWALL:P77727) (405 aa) fasta scores: E(): 6.9e-110, 64.46% id in 408 aa.
    
 0.822
murI
Putative glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
 
   
 0.770
BPSL2180
Putative membrane protein; Similar to Escherichia coli hypothetical protein YgeD or b2835 SWALL:YGED_ECOLI (SWALL:P39196) (397 aa) fasta scores: E(): 5.7e-21, 38.18% id in 419 aa, and to Ralstonia solanacearum probable transmembrane protein rsc1370 or rs04653 SWALL:Q8XZM5 (EMBL:AL646064) (438 aa) fasta scores: E(): 3.4e-123, 74.88% id in 438 aa.
 
     0.631
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
 
    0.580
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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