STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
Coexpression
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[Homology]
Score
astEPutative glutathione S-transferase (fragment); Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily. (349 aa)    
Predicted Functional Partners:
astB
Succinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2).
 
  
 0.994
astD
Succinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
 
 
 0.992
BPSL2388
Putative arginine N-succinyltransferase, beta chain; Similar to Escherichia coli, and Escherichia coli O157:H7 arginine N-succinyltransferase AstA SWALL:ASTA_ECOLI (SWALL:P76218) (344 aa) fasta scores: E(): 7.4e-60, 46.74% id in 338 aa, and to Pseudomonas aeruginosa arginine N-succinyltransferase, beta chain AruA or pa0897 SWALL:ASTG_PSEAE (SWALL:P80358) (340 aa) fasta scores: E(): 3.9e-53, 42.22% id in 341 aa, and to Pseudomonas aeruginosa arginine N-succinyltransferase, alpha chain AstA or AruF or pa0896 SWALL:ASTA_PSEAE (SWALL:P80357) (338 aa) fasta scores: E(): 2e-39, 37.13% id in [...]
 
  
 0.978
BPSL2389
Similar to Pseudomonas aeruginosa arginine N-succinyltransferase, alpha chain AstA or AruF or pa0896 SWALL:ASTA_PSEAE (SWALL:P80357) (338 aa) fasta scores: E(): 1e-52, 44.34% id in 336 aa, and to Escherichia coli, and Escherichia coli O157:H7 arginine N-succinyltransferase AstA SWALL:ASTA_ECOLI (SWALL:P76218) (344 aa) fasta scores: E(): 1.1e-36, 35.5% id in 338 aa, and to Pseudomonas aeruginosa arginine N-succinyltransferase, beta chain AruG or pa0897 SWALL:ASTG_PSEAE (SWALL:P80358) (340 aa) fasta scores: E(): 2e-36, 36.41% id in 346 aa.
 
  
 0.977
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
     
  0.900
putA
Bifunctional PutA protein [includes: proline dehydrogenase (EC 1.5.99.8) (proline oxidase); Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
     
  0.900
argM
Similar to Escherichia coli succinylornithine transaminase ArgM or AstC or CstC SWALL:ARGM_ECOLI (SWALL:P77581) (406 aa) fasta scores: E(): 5.3e-93, 61.38% id in 404 aa, and to Vibrio cholerae acetylornithine aminotransferase vc2618 SWALL:Q9KNW2 (EMBL:AE004328) (403 aa) fasta scores: E(): 1.4e-94, 60.55% id in 398 aa; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
  
 0.874
BPSL2925
Putative glutamate dehydrogenase; Similar to Bacillus subtilis NAD-specific glutamate dehydrogenase GudB SWALL:GUDB_BACSU (SWALL:P50735) (426 aa) fasta scores: E(): 2.1e-70, 47.51% id in 402 aa, and to Salmonella typhimurium putative homolog of glutamic dehyrogenase stm1795 SWALL:Q8ZP21 (EMBL:AE008780) (441 aa) fasta scores: E(): 2.4e-109, 64.67% id in 419 aa; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.807
glnA
Similar to Escherichia coli glutamine synthetase GlnA SWALL:GLNA_ECOLI (SWALL:P06711) (468 aa) fasta scores: E(): 3.4e-133, 65.51% id in 464 aa, and to Ralstonia solanacearum probable glutamine synthetase protein rsc1258 or rs02774 SWALL:Q8XZY7 (EMBL:AL646063) (471 aa) fasta scores: E(): 2e-175, 85.77% id in 471 aa.
     
  0.800
BPSL2336
Putative glutamine synthetase; Similar to Pseudomonas aeruginosa probable glutamine synthetase pa0298 SWALL:Q9I6J3 (EMBL:AE004467) (452 aa) fasta scores: E(): 1.2e-104, 55.35% id in 448 aa, and to Caulobacter crescentus glutamine synthetase family protein cc3130 SWALL:Q9A3S2 (EMBL:AE005976) (465 aa) fasta scores: E(): 2.5e-109, 61.53% id in 442 aa. BPSS0469, 87.838% identity (87.838% ungapped) in 444 aa overlap.
     
  0.800
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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