STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acpSPutative holo-[acyl-carrier protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (143 aa)    
Predicted Functional Partners:
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
    
 0.913
pdxJ
Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
 
  
 0.893
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
   
 
 0.851
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
  
 0.810
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
       0.762
BPSL2229
Similar to Pseudomonas putida siderophore non-ribosomal peptide synthetase PpsD SWALL:Q9AKS6 (EMBL:AJ310530) (2246 aa) fasta scores: E(): 4.8e-102, 28.54% id in 2659 aa, and to the C-terminal region of Pseudomonas syringae syringomycin synthetase SyrE SWALL:O85168 (EMBL:AF047828) (9376 aa) fasta scores: E(): 1.5e-94, 27.02% id in 3648 aa.
  
 
 0.736
BPSS1269
Putative peptide synthase/polyketide synthase; Similar to C-terminus of Aphanizomenon ovalisporum peptide synthetase AoaB SWALL:AAM33468 (EMBL:AF395828) (1869 aa) fasta scores: E(): 5.4e-125, 35.68% id in 1841 aa, and to C-terminus of Stigmatella aurantiaca MtaD SWALL:Q9RFK8 (EMBL:AF188287) (3291 aa) fasta scores: E(): 7.3e-124, 29.54% id in 3368 aa.
  
 
 0.736
BPSS1008
Putative polyketide synthase; N-terminal region is similar to the the N-terminal region of Bacillus subtilis putative polyketide synthase PksK SWALL:PKSK_BACSU (SWALL:P40803) (4447 aa) fasta scores: E(): 1.1e-167, 38.79% id in 3439 aa. Internal region is similar to an internal region of Pseudomonas fluorescens MmpIV protein SWALL:Q8RL72 (EMBL:AF318063) (6521 aa) fasta scores: E(): 2.8e-41, 32.83% id in 4069 aa.
  
 
 0.735
nagZ
Putative beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
       0.715
BPSL1712
Putative non-ribosomal antibiotic-related peptide synthase; Similar to Pseudomonas syringae syringomycin synthetase SyrE SWALL:O85168 (EMBL:AF047828) (9376 aa) fasta scores: E(): 1.5e-105, 31.93% id in 6198 aa, and to all the domains of Bacillus brevis tyrocidine synthetase III TycC SWALL:TYCC_BACBR (SWALL:O30409) blast scores: E(): 0.0, score: 4799 27% id. Note: Taking into consideration the blastp similarities and all the similarities to the domains in Bacillus brevis TycC, it could be proposed that BSPL1712 possibly incorporates six amino acids (Asn, Gln, Tyr, Val, Orn and Leu) into [...]
   
 
 0.711
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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