STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSL2467Similar to Ralstonia solanacearum hypothetical protein rsc0789 or rs05048 SWALL:Q8Y1A1 (EMBL:AL646061) (73 aa) fasta scores: E(): 5.3e-17, 66.66% id in 72 aa, and to Xanthomonas campestris hypothetical protein xcc2645 SWALL:AAM41917 (EMBL:AE012376) (80 aa) fasta scores: E(): 1.2e-12, 62.31% id in 69 aa. (73 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]
  
  
 0.521
norM
Putative multidrug resistance protein; Multidrug efflux pump; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
  
    0.510
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
  
  
 0.410
BPSL2819
Similar to Ralstonia solanacearum hypothetical protein rsc2625 or rs00929 SWALL:Q8XW50 (EMBL:AL646071) (233 aa) fasta scores: E(): 2.9e-43, 53.04% id in 230 aa, and to Neisseria meningitidis dnaA-related protein nmb1076 SWALL:Q9JZF5 (EMBL:AE002458) (222 aa) fasta scores: E(): 6.8e-22, 37.22% id in 231 aa, and to Neisseria meningitidis hypothetical protein Nma1279 SWALL:Q9JUJ9 (EMBL:AL162755) (243 aa) fasta scores: E(): 7.3e-22, 37.22% id in 231 aa.
  
  
 0.410
BPSL2479
Similar to Ralstonia solanacearum hypothetical protein rsc0944 or rs04461 SWALL:Q8Y0U9 (EMBL:AL646061) (208 aa) fasta scores: E(): 2.8e-32, 52.65% id in 207 aa, and to Vibrio cholerae hypothetical protein vc2536 SWALL:Q9KP43 (EMBL:AE004323) (193 aa) fasta scores: E(): 2.9e-18, 38.91% id in 203 aa; Belongs to the UPF0307 family.
  
   
 0.401
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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