STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSL2486Similar to Ralstonia solanacearum hypothetical protein rsc0937 or rs04477 SWALL:Q8Y0V6 (EMBL:AL646061) (202 aa) fasta scores: E(): 4.9e-42, 60.69% id in 201 aa, and to Brucella melitensis phosphohydrolase bmei0462 SWALL:Q8YII2 (EMBL:AE009489) (207 aa) fasta scores: E(): 8.2e-29, 48.5% id in 200 aa. (227 aa)    
Predicted Functional Partners:
nnrE
Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...]
  
 0.893
cobD-2
Putative membrane protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
       0.652
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
 0.604
rnr
Putative ribonuclease; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
   
 0.572
BPSL2977
Similar to Escherichia coli exoribonuclease II Rnb or b1286 SWALL:RNB_ECOLI (SWALL:P30850) (644 aa) fasta scores: E(): 2e-08, 28.45% id in 355 aa, and to Neisseria meningitidis ribonuclease II-related protein nmb0282 SWALL:Q9K185 (EMBL:AE002385) (626 aa) fasta scores: E(): 2.2e-64, 39.9% id in 644 aa.
   
 0.572
BPSL1863
Similar to Ralstonia solanacearum hypothetical protein rsc1618 or rs03981 SWALL:Q8XYY8 (EMBL:AL646065) (195 aa) fasta scores: E(): 2.6e-54, 71.19% id in 184 aa, and to Pseudomonas aeruginosa hypothetical protein pa3755 SWALL:Q9HXP0 (EMBL:AE004794) (184 aa) fasta scores: E(): 4.4e-46, 65.08% id in 169 aa; Belongs to the Nudix hydrolase family.
 
  
 0.515
BPSL0763
Putative helicase SNF2 family protein; Similar to Bacteroides nodosus putative DEAH ATP-dependent helicase SWALL:O32494 (EMBL:U20246) (965 aa) fasta scores: E(): 2.4e-28, 28.84% id in 780 aa, and to Xanthomonas campestris helicase xcc0524 SWALL:AAM39840 (EMBL:AE012150) (967 aa) fasta scores: E(): 1.8e-11, 25.36% id in 962 aa, and to Halobacterium sp. similar to Escherichia coli vng5141g or vng6139G SWALL:O52003 (EMBL:AF016485) (979 aa) fasta scores: E(): 1.9e-10, 27.33% id in 995 aa. Possible alternative translational start site.
  
 0.467
BPSL2004
Putative phosphatase; Similar to Ralstonia solanacearum hypothetical protein rsc0809 or rs05013 SWALL:Q8Y181 (EMBL:AL646061) (193 aa) fasta scores: E(): 3.4e-45, 64.24% id in 179 aa, and to Pseudomonas aeruginosa NADH pyrophosphatase NudC or pa1823 SWALL:NUDC_PSEAE (SWALL:O86062) (278 aa) fasta scores: E(): 2.1e-05, 27.1% id in 166 aa.
 
   
 0.436
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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