STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UreDUreD-family accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (332 aa)    
Predicted Functional Partners:
ureF
Urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.995
ureB
Urease beta subunit; Similar to Bordetella bronchiseptica urease beta subunit UreB SWALL:URE2_BORBR (SWALL:O06707) (102 aa) fasta scores: E(): 3.2e-24, 64.35% id in 101 aa, and to Pseudomonas aeruginosa urease beta subunit UreB or pa4867 SWALL:Q9HUU6 (EMBL:AE004900) (101 aa) fasta scores: E(): 2.8e-28, 76.23% id in 101 aa.
 
 
 0.984
ureG
Urease accessory protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.980
ureA
Urease gamma subunit; Similar to Bordetella bronchiseptica Urease gamma subunit UreA SWALL:URE3_BORBR (SWALL:O06705) (100 aa) fasta scores: E(): 3.3e-29, 82.82% id in 99 aa, and to Alcaligenes eutrophus Urease, structural subunit UreA SWALL:O30334 (EMBL:Y13732) (100 aa) fasta scores: E(): 1.5e-30, 85.85% id in 99 aa.
 
 
 0.977
ureE
Urease accessory protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.942
ureC
Urease alpha subunit; Similar to Synechocystis sp. urease alpha subunit UreC or sll1750 SWALL:URE1_SYNY3 (SWALL:P73061) (569 aa) fasta scores: E(): 3.3e-166, 74.86% id in 569 aa, and to Alcaligenes eutrophus urease, structural subunit UreC SWALL:O30337 (EMBL:Y13732) (570 aa) fasta scores: E(): 3.3e-185, 83.12% id in 569 aa; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
 
  
 0.923
BPSL2654
Similar to Yersinia pestis putative ABC transport ATP-binding subunit ypo1190 SWALL:Q8ZGT7 (EMBL:AJ414147) (278 aa) fasta scores: E(): 8.5e-43, 61.22% id in 245 aa, and to Ralstonia solanacearum probable ATP-binding ABC transporter protein rsc2038 or rs03603 SWALL:Q8XXS5 (EMBL:AL646067) (287 aa) fasta scores: E(): 2e-63, 72.69% id in 282 aa.
 
   
 0.842
BPSL2652
Similar to Yersinia pestis putative branched-chain amino acid transport system, permease component ypo1188 SWALL:Q8ZGT9 (EMBL:AJ414147) (533 aa) fasta scores: E(): 1.3e-79, 50.48% id in 515 aa and to Ralstonia solanacearum probable permease transporter transmembrane protein rsc2040 or rs03605 SWALL:Q8XXS3 (EMBL:AL646067) (538 aa) fasta scores: E(): 3.8e-109, 64.2% id in 542 aa.
 
   
 0.828
BPSL2653
Similar to Yersinia pestis putative branched-chain amino acid transport system, permease component ypo1189 SWALL:Q8ZGT8 (EMBL:AJ414147) (358 aa) fasta scores: E(): 2.4e-77, 62.17% id in 341 aa, and to Ralstonia solanacearum probable permease transporter transmembrane protein rsc2039 or rs03604 SWALL:Q8XXS4 (EMBL:AL646067) (396 aa) fasta scores: E(): 1.1e-100, 74.86% id in 362 aa.
 
   
 0.828
BPSL2651
Putative exported protein; Similar to Ralstonia solanacearum putative urea/short-chain amide-binding signal peptide protein rsc2041 or rs03606 SWALL:Q8XXS2 (EMBL:AL646067) (418 aa) fasta scores: E(): 7.9e-133, 82.61% id in 420 aa and to Yersinia pestis putative substrate-binding periplasmic transport protein ypo1187 SWALL:Q8ZGU0 (EMBL:AJ414147) (422 aa) fasta scores: E(): 8.5e-121, 76.42% id in 420 aa.
 
   
 0.827
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.