STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureCUrease alpha subunit; Similar to Synechocystis sp. urease alpha subunit UreC or sll1750 SWALL:URE1_SYNY3 (SWALL:P73061) (569 aa) fasta scores: E(): 3.3e-166, 74.86% id in 569 aa, and to Alcaligenes eutrophus urease, structural subunit UreC SWALL:O30337 (EMBL:Y13732) (570 aa) fasta scores: E(): 3.3e-185, 83.12% id in 569 aa; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (568 aa)    
Predicted Functional Partners:
ureA
Urease gamma subunit; Similar to Bordetella bronchiseptica Urease gamma subunit UreA SWALL:URE3_BORBR (SWALL:O06705) (100 aa) fasta scores: E(): 3.3e-29, 82.82% id in 99 aa, and to Alcaligenes eutrophus Urease, structural subunit UreA SWALL:O30334 (EMBL:Y13732) (100 aa) fasta scores: E(): 1.5e-30, 85.85% id in 99 aa.
 0.999
ureB
Urease beta subunit; Similar to Bordetella bronchiseptica urease beta subunit UreB SWALL:URE2_BORBR (SWALL:O06707) (102 aa) fasta scores: E(): 3.2e-24, 64.35% id in 101 aa, and to Pseudomonas aeruginosa urease beta subunit UreB or pa4867 SWALL:Q9HUU6 (EMBL:AE004900) (101 aa) fasta scores: E(): 2.8e-28, 76.23% id in 101 aa.
 0.999
ureF
Urease accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.996
ureE
Urease accessory protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.994
ureG
Urease accessory protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.991
UreD
UreD-family accessory protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
  
 0.923
BPSS0195
Similar to Pseudomonas aeruginosa hypothetical protein pa0495 SWALL:Q9I623 (EMBL:AE004486) (292 aa) fasta scores: E(): 5.2e-84, 69.55% id in 289 aa, and to parts of Pseudomonas fluorescens urea amidolyase homologue UahA SWALL:Q9XAV3 (EMBL:AJ243652) (1213 aa) fasta scores: E(): 4.9e-13, 26.18% id in 275 aa.
     
 0.909
alc1
Similar to Ralstonia solanacearum putative allantoicase rsc3274 or rs02503 SWALL:Q8XUB7 (EMBL:AL646074) (336 aa) fasta scores: E(): 2.8e-115, 77.67% id in 336 aa, and to Schizosaccharomyces pombe probable allantoicase spac1f7.09C SWALL:ALC_SCHPO (SWALL:Q09913) (342 aa) fasta scores: E(): 5.7e-49, 44.03% id in 327 aa; Belongs to the allantoicase family.
    
  0.907
alc2
Similar to Ralstonia solanacearum putative allantoicase rsc3274 or rs02503 SWALL:Q8XUB7 (EMBL:AL646074) (336 aa) fasta scores: E(): 4.2e-106, 74.62% id in 335 aa, and to Streptomyces coelicolor putative allantoicase sco6248 or scah10.13 or stah10.13 SWALL:ALC_STRCO (SWALL:Q9RKU4) (376 aa) fasta scores: E(): 3.3e-28, 43.82% id in 340 aa; Belongs to the allantoicase family.
    
  0.907
allA
Putative ureidoglycolate hydrolase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
    
  0.902
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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