STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcnBPutative polynucleotide adenylyltransferase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (515 aa)    
Predicted Functional Partners:
BPSL2822
Similar to Escherichia coli 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FolK or b0142 SWALL:HPPK_ECOLI (SWALL:P26281) (158 aa) fasta scores: E(): 1.7e-13, 39.35% id in 155 aa, and to Ralstonia solanacearum probable 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase protein FolK or rsc2628 or rs00932 SWALL:Q8XW47 (EMBL:AL646071) (169 aa) fasta scores: E(): 2e-41, 62.13% id in 169 aa, and to Bacillus halodurans 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FolK or bh0095 SW [...]
  
  
 0.910
BPSL2820
Conserved hypothetical protein; Similar to Ralstonia solanacearum putative hydrolase protein rsc2626 or rs00930 SWALL:Q8XW49 (EMBL:AL646071) (224 aa) fasta scores: E(): 3.6e-62, 65.47% id in 223 aa, and to Neisseria meningitidis hypothetical protein Nmb1075 SWALL:Q9JZF6 (EMBL:AE002458) (222 aa) fasta scores: E(): 2.9e-40, 47.32% id in 224 aa, and to Neisseria meningitidis hypothetical protein Nma1278 SWALL:Q9JUK0 (EMBL:AL162755) (222 aa) fasta scores: E(): 4.6e-40, 46.87% id in 224 aa.
 
  
 0.873
BPSL2819
Similar to Ralstonia solanacearum hypothetical protein rsc2625 or rs00929 SWALL:Q8XW50 (EMBL:AL646071) (233 aa) fasta scores: E(): 2.9e-43, 53.04% id in 230 aa, and to Neisseria meningitidis dnaA-related protein nmb1076 SWALL:Q9JZF5 (EMBL:AE002458) (222 aa) fasta scores: E(): 6.8e-22, 37.22% id in 231 aa, and to Neisseria meningitidis hypothetical protein Nma1279 SWALL:Q9JUJ9 (EMBL:AL162755) (243 aa) fasta scores: E(): 7.3e-22, 37.22% id in 231 aa.
 
 
 
 0.853
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
 
 
 0.812
mgsA
Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
  
  
 0.745
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.717
BPSL2823
Putative deoxyguanosine kinase/deoxyadenosine kinase; Similar to Lactobacillus acidophilus deoxyadenosine kinase SWALL:DGK1_LACAC (SWALL:Q59483) (214 aa) fasta scores: E(): 6.5e-08, 26.94% id in 193 aa, and to Ralstonia solanacearum putative deoxyguanosine kinase rsc2629 or rs00933 SWALL:Q8XW46 (EMBL:AL646071) (214 aa) fasta scores: E(): 6.4e-27, 47.29% id in 203 aa, and to uncultured proteobacterium EBAC31A08 predicted deoxypurine kinase SWALL:Q9F7R4 (EMBL:AF279106) (221 aa) fasta scores: E(): 1.5e-24, 42.92% id in 205 aa, and to Deinococcus radiodurans subunit dr0299 SWALL:Q9RXL1 (EM [...]
       0.701
miaA
Putative tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
 
  
 0.687
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
  
    0.685
hfq
Hfq protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
    
 
 0.678
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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