STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gidBMethyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (230 aa)    
Predicted Functional Partners:
gidA
Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
 
  
 0.993
trmE
Putative tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
  
 0.966
BPSL3405
Similar to Ralstonia solanacearum putative chromosome partitioning protein ParB or Rsc3325 or Rs02555 SWALL:Q8XU68 (EMBL:AL646074) (303 aa) fasta scores: E(): 2.3e-72, 73.12% id in 294 aa, and to Caulobacter crescentus chromosome partitioning protein ParB or Cc3752 SWALL:PARB_CAUCR (SWALL:O05190) (294 aa) fasta scores: E(): 3.8e-32, 42.42% id in 297 aa; Belongs to the ParB family.
  
  
 0.881
BPSL3406
Similar to Ralstonia solanacearum putative chromosome partitioning protein ParA or rsc3326 or Rs02560 SWALL:Q8XU67 (EMBL:AL646074) (261 aa) fasta scores: E(): 3.2e-75, 79.29% id in 256 aa, and to Caulobacter crescentus chromosome partitioning protein ParA or Cc3753 SWALL:PARA_CAUCR (SWALL:O05189) (267 aa) fasta scores: E(): 1.8e-43, 49.21% id in 254 aa.
  
  
 0.802
rpsF
Putative 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
 
   
 0.734
BPSS2350
Putative partitioning protein ParB; C-terminal region is similar to the C-terminal region of Ralstonia solanacearum putative partitioning protein rsp0004 or rs01976 SWALL:Q8XTV0 (EMBL:AL646076) (334 aa) fasta scores: E(): 2.6e-19, 31.06% id in 264 aa, and to the full length Bacillus subtilis stage 0 sporulation protein J Spo0J SWALL:SP0J_BACSU (SWALL:P26497) (282 aa) fasta scores: E(): 4.4e-06, 24.35% id in 271 aa; Belongs to the ParB family.
  
  
 0.705
rpsL
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
      
 0.702
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
     0.668
der
Putative GTPase; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
     0.638
BPSL2956
Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
 
  
 0.635
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.