STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSS0540Similar to Xanthomonas axonopodis outer membrane efflux protein xac1444 SWALL:AAM36315 (EMBL:AE011776) (496 aa) fasta scores: E(): 7.2e-38, 38.41% id in 505 aa, and to Burkholderia cepacia fusaric acid resistance protein fusa precursor FusA SWALL:FUSA_BURCE (SWALL:P24126) (530 aa) fasta scores: E(): 9.3e-28, 31.74% id in 526 aa. Identical to BPSS1348, 100.000% identity (100.000% ungapped) in 527 aa overlap. (527 aa)    
Predicted Functional Partners:
macB
Macrolide-specific ABC-type efflux carrier; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.808
BPSS1347
Similar to Neisseria gonorrhoeae efflux pump protein FarA SWALL:Q9RQ30 (EMBL:AF132909) (394 aa) fasta scores: E(): 6.5e-48, 48.46% id in 359 aa, and to Ralstonia solanacearum probable multidrug resistance A EmrA or rsc1293 or rs02806 SWALL:Q8XZV2 (EMBL:AL646063) (428 aa) fasta scores: E(): 6e-57, 47.76% id in 402 aa, and to Xanthomonas campestris multidrug resistance efflux pump PmrA or xcc1399 SWALL:AAM40697 (EMBL:AE012239) (397 aa) fasta scores: E(): 1.1e-49, 44.22% id in 398 aa.
 
 
 0.763
BPSS0541
HlyD family secretion protein; Similar to Escherichia coli multidrug resistance protein A EmrA SWALL:EMRA_ECOLI (SWALL:P27303) (390 aa) fasta scores: E(): 9e-46, 40.51% id in 390 aa, and to Xanthomonas campestris multidrug resistance efflux pump xcc1399 SWALL:AAM40697 (EMBL:AE012239) (397 aa) fasta scores: E(): 5.4e-50, 44.44% id in 387 aa. Almost identical to BPSS1347, 99.742% identity (99.742% ungapped) in 388 aa overlap.
 
 
 0.761
emrA
Similar to Escherichia coli multidrug resistance protein A EmrA or b2685 SWALL:EMRA_ECOLI (SWALL:P27303) (390 aa) fasta scores: E(): 1e-62, 49.74% id in 390 aa, and to Ralstonia solanacearum probable multidrug resistance A EmrA or rsc1293 or rs02806 SWALL:Q8XZV2 (EMBL:AL646063) (428 aa) fasta scores: E(): 1.2e-87, 63.48% id in 408 aa.
 
 
 0.752
bpeA
Similar to Escherichia coli, and Escherichia coli O157:H7 acriflavine resistance protein A precursor acrA or MtcA or Lir SWALL:ACRA_ECOLI (SWALL:P31223) (397 aa) fasta scores: E(): 5.5e-60, 53.76% id in 385 aa, and to Ralstonia solanacearum probable acriflavin resistance lipoprotein A precursor rsc0011 or rs01833 SWALL:Q8Y3G9 (EMBL:AL646057) (398 aa) fasta scores: E(): 6.6e-61, 55.22% id in 402 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.683
amrA
Almost identical to Burkholderia pseudomallei putative membrane fusion protein AmrA SWALL:O87935 (EMBL:AF072887) (399 aa) fasta scores: E(): 7.7e-133, 99.74% id in 399 aa. Similar to Escherichia coli, and Escherichia coli O157:H7 acriflavine resistance protein A precursor AcrA or MtcA or Lir or b0463 or z0578 or ecs0516 SWALL:ACRA_ECO57 (SWALL:P31223) (397 aa) fasta scores: E(): 3.5e-43, 40.1% id in 384 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.669
BPSL2020
HlyD family secretion protein; Similar to Escherichia coli multidrug resistance protein K EmrK or b2368 SWALL:EMRK_ECOLI (SWALL:P52599) (387 aa) fasta scores: E(): 1.7e-18, 31.65% id in 357 aa, and to Rhizobium meliloti hypothetical protein rb1406 or smb20699 SWALL:Q92TT9 (EMBL:AL603647) (365 aa) fasta scores: E(): 5.4e-33, 38.71% id in 372 aa, and to Pseudomonas putida TrpB trpB SWALL:Q8RPR5 (EMBL:AF360362) (353 aa) fasta scores: E(): 3.2e-32, 38.75% id in 338 aa. Note: This CDS is longer in its N-terminal region than most of its database matches.
 
 
 0.638
BPSS0292
Putative multidrug efflux system exported protein; Similar to Escherichia coli, and Escherichia coli O157:H7 acriflavine resistance protein A precursor AcrA or MtcA or Lir or b0463 or z0578 or ecs0516 SWALL:ACRA_ECOLI (SWALL:P31223) (397 aa) fasta scores: E(): 5.3e-33, 32.98% id in 385 aa, and to Ralstonia solanacearum probable transmembrane multidrug efflux system transmembrane protein ys02620 or rsp1112 or rs02620 SWALL:Q8XQV6 (EMBL:AL646082) (438 aa) fasta scores: E(): 6.1e-78, 57.77% id in 405 aa; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.606
BPSL2234
Putative exported protein; Similar to Escherichia coli hypothetical protein precursor YegM or b2074 SWALL:YEGM_ECOLI (SWALL:P76397) (415 aa) fasta scores: E(): 2.5e-37, 36.29% id in 405 aa, and to Rhizobium loti RND efflux membrane fusion protein mll5780 SWALL:Q98B05 (EMBL:AP003007) (417 aa) fasta scores: E(): 1.5e-35, 34.54% id in 414 aa.
 
 
 0.580
BPSS1252
Putative inner membrane transport protein; Similar to Escherichia coli shikimate transporter ShiA or b1981 SWALL:SHIA_ECOLI (SWALL:P76350) (438 aa) fasta scores: E(): 5.4e-52, 36.34% id in 421 aa, and to Pseudomonas aeruginosa probable MFS transporter pa3595 SWALL:Q9HY31 (EMBL:AE004780) (469 aa) fasta scores: E(): 2.9e-66, 44.17% id in 446 aa, and to Rhodococcus sp putative 3- ohpA SWALL:Q9KH22 (EMBL:AF274045) (468 aa) fasta scores: E(): 8.3e-59, 40.54% id in 439 aa.
   
  
 0.580
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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