STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BPSS0691MarR family regulator protein; Similar to Escherichia coli, and Shigella flexneri homoprotocatechuate degradative operon repressor HpcR or HpaR SWALL:HPCR_ECOLI (SWALL:Q07095) (148 aa) fasta scores: E(): 6.2e-20, 46.04% id in 139 aa, and to Ralstonia solanacearum probable transcription regulator protein rsc1592 or rs03954 SWALL:Q8XZ14 (EMBL:AL646065) (154 aa) fasta scores: E(): 5.6e-21, 47.18% id in 142 aa. (145 aa)    
Predicted Functional Partners:
hpcB
Similar to Escherichia coli 3,4-dihydroxyphenylacetate 2,3-dioxygenase HpcB SWALL:HPCB_ECOLI (SWALL:Q05353) (275 aa) fasta scores: E(): 7e-71, 64.09% id in 259 aa, and to Salmonella typhi 3,4-dihydroxyphenylacetate 2,3-dioxygenase sty1137 SWALL:Q8Z7Q1 (EMBL:AL627269) (283 aa) fasta scores: E(): 6.1e-81, 66.31% id in 282 aa.
 
   
 0.854
hpcD
Similar to Escherichia coli 5-carboxymethyl-2-hydroxymuconate delta-isomerase HpcD SWALL:HPCD_ECOLI (SWALL:Q05354) (125 aa) fasta scores: E(): 2e-18, 48.41% id in 126 aa, and to Ralstonia solanacearum putative 5-carboxymethyl-2-hydroxymuconate delta-isomerase protein rsc2419 or rs02694 SWALL:Q8XWQ4 (EMBL:AL646070) (134 aa) fasta scores: E(): 2.6e-24, 50.79% id in 126 aa.
 
   
 0.840
hpcG
Similar to Escherichia coli 2-oxo-hepta-3-ene-1,7-dioic acid hydratase HpcG SWALL:HPCG_ECOLI (SWALL:P42270) (264 aa) fasta scores: E(): 3.3e-74, 70.3% id in 266 aa, and to Salmonella typhimurium, and Salmonella typhi 4-hydroxyphenylacetate catabolism stm1105 or sty1139 SWALL:Q8XGD0 (EMBL:AE008748) (267 aa) fasta scores: E(): 1.4e-80, 74.06% id in 266 aa.
 
     0.784
BPSS0165
Putative dioxygenase; Similar to Salmonella typhi 3,4-dihydroxyphenylacetate 2,3-dioxygenase sty1137 SWALL:Q8Z7Q1 (EMBL:AL627269) (283 aa) fasta scores: E(): 6.7e-18, 29.21% id in 291 aa, and to Escherichia coli 3,4-dihydroxyphenylacetate 2,3-dioxygenase HpcB SWALL:HPCB_ECOLI (SWALL:Q05353) (275 aa) fasta scores: E(): 4.2e-16, 28.95% id in 259 aa.
 
   
 0.705
hpcH
Similar to Escherichia coli 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase HpcH or HpaI SWALL:HPAI_ECOLI (SWALL:Q47098) (262 aa) fasta scores: E(): 9.1e-58, 67.3% id in 260 aa, and to Ralstonia solanacearum putative 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase oxidoreductase protein rsc1591 or rs03953 SWALL:Q8XZ15 (EMBL:AL646065) (272 aa) fasta scores: E(): 4.4e-61, 69.61% id in 260 aa; Belongs to the HpcH/HpaI aldolase family.
 
   
 0.703
hpcC
Similar to Escherichia coli 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase HpcC SWALL:HPCC_ECOLI (SWALL:P42269) (468 aa) fasta scores: E(): 2.7e-138, 75.05% id in 461 aa, and to Pseudomonas aeruginosa 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase pa4123 SWALL:Q9HWQ8 (EMBL:AE004828) (486 aa) fasta scores: E(): 3.2e-161, 81.85% id in 485 aa.
 
     0.651
BPSS0692
Fumarylacetoacetate (FAA) hydrolase family protein; Similar to Pseudomonas aeruginosa hypothetical protein pa4121 SWALL:Q9HWR0 (EMBL:AE004828) (219 aa) fasta scores: E(): 6.1e-30, 42.92% id in 212 aa, and to the N-terminal region of Escherichia coli 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase [includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase] HpaG SWALL:HPAG_ECOLI (SWALL:Q46978) (429 aa) fasta scores: E(): 1.6e-21, 33.97% id in 209 aa.
 
     0.645
BPSS0693
Fumarylacetoacetate (FAA) hydrolase family protein; Similar to Pseudomonas aeruginosa hypothetical protein pa4122 SWALL:Q9HWQ9 (EMBL:AE004828) (259 aa) fasta scores: E(): 4.6e-59, 59.68% id in 253 aa, and to the C-terminal region of Escherichia coli 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase [includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase; 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase] HpaG SWALL:HPAG_ECOLI (SWALL:Q46978) (429 aa) fasta scores: E(): 4.9e-47, 58.29% id in 223 aa.
 
     0.633
BPSL0180
HpcH/HpaI aldolase family protein; Similar to Escherichia coli 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase HpcH or HpaI SWALL:HPAI_ECOLI (SWALL:Q47098) (262 aa) fasta scores: E(): 1.6e-31, 44.57% id in 249 aa, and to Escherichia coli 2-dehydro-3-deoxyglucarate aldolase GarL SWALL:GARL_ECOLI (SWALL:P23522) (256 aa) fasta scores: E(): 6e-32, 46.21% id in 238 aa; Belongs to the HpcH/HpaI aldolase family.
 
   
 0.474
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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