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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
selAL-seryl-tRNA(SeC) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (480 aa)    
Predicted Functional Partners:
selD
Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP.
 
  
 0.985
selB
Similar to Escherichia coli selenocysteine-specific elongation factor SelB or FdhA or b3590 SWALL:SELB_ECOLI (SWALL:P14081) (614 aa) fasta scores: E(): 1.4e-43, 42.45% id in 636 aa, and to Pseudomonas aeruginosa selenocysteine-specific elongation factor SelB or pa4807 SWALL:Q9HV02 (EMBL:AE004893) (641 aa) fasta scores: E(): 5.8e-97, 49.76% id in 639 aa.
 
  
 0.970
fdhE
Protein FdhE; Necessary for formate dehydrogenase activity. Belongs to the FdhE family.
 
   
 0.958
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
     
 0.930
fdoG
Similar to Escherichia coli formate dehydrogenase-O, major subunit Fdog or b3894 SWALL:FDOG_ECOLI (SWALL:P32176) (1016 aa) fasta scores: E(): 0, 66.6% id in 1021 aa, and to Shigella flexneri formate dehydrogenase-O, major subunit Fdog or sf3970 SWALL:AAN45405 (EMBL:AE015404) (1016 aa) fasta scores: E(): 0, 66.69% id in 1021 aa. This CDS contains an in-frame opal codon, UGA, at position 197. This opal codon encodes selenocysteine, which forms the active-site of the protein.
 
   
 0.903
fdoH
Formate dehydrogenase-O, iron-sulfur subunit; Similar to Escherichia coli, Escherichia coli O6, and Shigella flexneri formate dehydrogenase-O, iron-sulfur subunit FdoH or b3893 or c4843 or sf3969 SWALL:FDOH_ECOLI (SWALL:P32175) (300 aa) fasta scores: E(): 2.4e-81, 68.21% id in 302 aa, and to Yersinia pestis formate dehydrogenase-o, iron-sulfur subunit fdoh or ypo4057 or y4077 SWALL:Q8Z9X8 (EMBL:AJ414160) (323 aa) fasta scores: E(): 1.8e-84, 72.26% id in 292 aa.
 
   
 0.894
fdoI
Formate dehydrogenase, cytochrome b556 (FDO) subunit; Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 formate dehydrogenase, cytochrome B556 (FDO) subunit FdoI or b3892 or c4842 or z5434 or ecs4818 SWALL:FDOI_ECOLI (SWALL:P32174) (211 aa) fasta scores: E(): 4.6e-42, 54.32% id in 208 aa, and to Pseudomonas aeruginosa nitrate-inducible formate dehydrogenase, gamma subunit FdnI or pa4810 SWALL:Q9HUZ9 (EMBL:AE004894) (208 aa) fasta scores: E(): 1e-50, 62.81% id in 199 aa.
 
  
 0.878
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
      
 0.714
moaD
Similar to Escherichia coli molybdopterin converting factor subunit 1 MoaD or ChlA4 or ChlM or b0784 SWALL:MOAD_ECOLI (SWALL:P30748) (81 aa) fasta scores: E(): 1.1e-05, 40.96% id in 83 aa, and to Ralstonia solanacearum probable molybdopterin converting factor rsc1331 or rs02853 SWALL:Q8XZR4 (EMBL:AL646064) (87 aa) fasta scores: E(): 7.8e-20, 65.88% id in 85 aa.
   
   0.586
aspS
aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
      
 0.575
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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