STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
udg2UDP-glucose 6-dehydrogenase 2; Similar to Pseudomonas aeruginosa UDP-glucose 6-dehydrogenase Udg or Ugd or pa2022 SWALL:UDG_PSEAE (SWALL:O86422) (453 aa) fasta scores: E(): 5.7e-83, 51.97% id in 456 aa, and to Rhizobium meliloti UDP-glucose 6-dehydrogenase RkpK or r01082 or smc02641 SWALL:UDG_RHIME (SWALL:O54068) (437 aa) fasta scores: E(): 2.8e-70, 49.66% id in 453 aa. Note: Also similar to BPSL2511 Udg (467 aa) fasta scores: E(): 1.5e-121, 76.304% identity in 460 aa overlap. (473 aa)    
Predicted Functional Partners:
BPSS2245
Putative epimerase; Similar to Pseudomonas aeruginosa similar to NAD dependent epimerase/dehydratase family SWALL:AAM27842 (EMBL:AF498418) (318 aa) fasta scores: E(): 1.4e-87, 69.5% id in 305 aa, and to Synechocystis sp. dTDP-glucose 4-6-dehydratase RfbB or slr0809 SWALL:P74036 (EMBL:D90911) (328 aa) fasta scores: E(): 1.6e-73, 61.09% id in 311 aa.
 0.976
galU
UTP--glucose-1-phosphate uridylyltransferase; Similar to Escherichia coli, Escherichia coli O157:H7, and Shigella flexneri UTP--glucose-1-phosphate uridylyltransferase GalU or b1236 or z2012 or ecs1738 SWALL:GALU_ECOLI (SWALL:P25520) (301 aa) fasta scores: E(): 5.6e-51, 54.82% id in 290 aa, and to Burkholderia pseudomallei putative UTP-glucose-1-phosphate uridylyltransferase SWALL:Q9F5N4 (EMBL:AF312223) (295 aa) fasta scores: E(): 2.7e-92, 83.91% id in 286 aa.
  
 0.955
BPSL2769
Putative UTP-glucose-1-phosphate uridylyltransferase; Similar to Xanthomonas campestris UDP-glucose pyrophosphorylase SWALL:P74969 (EMBL:U65532) (324 aa) fasta scores: E(): 5.2e-57, 57.72% id in 272 aa, and to previously sequenced Burkholderia pseudomallei putative UTP-glucose-1-phosphate uridylyltransferase SWALL:Q9F5N4 (EMBL:AF312223) (295 aa) fasta scores: E(): 9.6e-91, 78.15% id in 293 aa, and to Ralstonia solanacearum probable UTP-glucose-1-phosphate uridylyltransferase protein GalU1 or rsc2237 or rs01362 SWALL:Q8XX79 (EMBL:AL646069) (289 aa) fasta scores: E(): 2.3e-90, 77.16% id [...]
  
 0.945
gtaB
Putative UTP-glucose-1-phosphate uridylyltransferase; Similar to Bacillus subtilis UTP--glucose-1-phosphate uridylyltransferase GtaB SWALL:GTAB_BACSU (SWALL:Q05852) (292 aa) fasta scores: E(): 3.2e-52, 49.48% id in 289 aa, and to Burkholderia pseudomallei putative UTP-glucose-1-phosphate uridylyltransferase SWALL:Q9F5N4 (EMBL:AF312223) (295 aa) fasta scores: E(): 5.5e-114, 98.64% id in 295 aa.
  
 0.945
rmlC
dTDP-6-deoxy-D-glucose-3,5 epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
  
 0.932
BPSL2670
UDP-glucose 4-epimerase; Previously sequenced as Burkholderia pseudomallei putative UDP-glucose 4-epimerase SWALL:O69132 (EMBL:AF064070) (340 aa) fasta scores: E(): 3.1e-125, 100% id in 340 aa and similar to Bacillus subtilis UDP-glucose 4-epimerase GalE SWALL:GALE_BACSU (SWALL:P55180) (339 aa) fasta scores: E(): 6.8e-80, 65.16% id in 333 aa; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
 
 0.924
udg
Putative UDP-glucose dehydrogenase; Highly similar to the previously sequenced Burkholderia pseudomallei putative UDP-glucose dehydrogenase Udg SWALL:Q9WWX8 (EMBL:AF159428) (466 aa) fasta scores: E(): 1.1e-178, 99.35% id in 466 aa, and to Pseudomonas aeruginosa UDP-glucose 6-dehydrogenase Udg or pa2022 SWALL:UDG_PSEAE (SWALL:O86422) (453 aa) fasta scores: E(): 2.6e-86, 53.39% id in 457 aa. Note: Also similar to BPSS1833 (474 aa) fasta scores: E(): 1.5e-121, 76.304% identity in 460 aa overlap.
  
  
 
0.901
rmlB
dTDP-glucose 4,6-dehydratase; Previously sequenced as Burkholderia pseudomallei putative dTDP-D-glucose 4,6-dehydratase RmlB SWALL:O69116 (EMBL:AF064070) (353 aa) fasta scores: E(): 5.6e-143, 100% id in 353 aa and similar to Xanthomonas campestris dTDP-glucose 4,6-dehydratase RfbB or RmlB or xcc0621 SWALL:RFBB_XANCP (SWALL:P55295) (351 aa) fasta scores: E(): 1.2e-88, 66.56% id in 341 aa; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.889
rmlA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
  
 0.879
BPSS1834
Putative lipopolysaccharide biosynthesis related protein; Similar to Escherichia coli putative colanic biosynthesis UDP-glucose lipid carrier transferase WcaJ or b2047 SWALL:WCAJ_ECOLI (SWALL:P71241) (464 aa) fasta scores: E(): 2.5e-59, 39.65% id in 469 aa, and to Salmonella typhimurium putative undecaprenylphosphate glucosephosphotransferase WcaJ or stm2103 SWALL:Q9F799 (EMBL:AF285085) (464 aa) fasta scores: E(): 2.8e-58, 38.92% id in 465 aa. Note: Also similar to BPSL0618 (473 aa) fasta scores: E(): 3.5e-96, 50.433% identity in 462 aa overlap.
     
 0.804
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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