STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (260 aa)    
Predicted Functional Partners:
deoA
Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
 
 
 0.971
tktA
Transketolase 1; Similar to Escherichia coli transketolase 1 TktA or Tkt or b2935 SWALL:TKT1_ECOLI (SWALL:P27302) (663 aa) fasta scores: E(): 4.8e-167, 63.48% id in 671 aa, and to Ralstonia solanacearum probable transketolase protein rsc2750 or rs00104 SWALL:Q8XVS9 (EMBL:AL646071) (675 aa) fasta scores: E(): 4.5e-192, 72.99% id in 674 aa; Belongs to the transketolase family.
  
 0.940
talB
Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
    
 0.927
cbbA
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
    
 0.922
rbsK
Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
    
 0.914
rbsK-2
Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
    
 0.914
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.905
BPSL2223
Putative transketolase; Similar to Fusobacterium nucleatum transketolase subunit A fn0294 SWALL:Q8RGJ9 (EMBL:AE010542) (270 aa) fasta scores: E(): 2.2e-33, 42.53% id in 268 aa, and to Methanococcus jannaschii putative transketolase N-terminal section mj0681 SWALL:TKTN_METJA (SWALL:Q58094) (274 aa) fasta scores: E(): 2.5e-29, 38.62% id in 277 aa.
    
 0.903
BPSL2222
Putative transketolase; Similar to Thermoplasma acidophilum probable transketolase ta0617 SWALL:Q9HKI2 (EMBL:AL445064) (316 aa) fasta scores: E(): 2.6e-24, 32.67% id in 303 aa, and to Pyrococcus abyssi transketolase C-terminal section Tkt2 or pab0296 SWALL:Q9V1I1 (EMBL:AJ248284) (317 aa) fasta scores: E(): 9.6e-22, 32.65% id in 294 aa.
  
 
  0.901
gapA
Similar to Bacillus subtilis glyceraldehyde 3-phosphate dehydrogenase 1 AapA or Gap SWALL:G3P1_BACSU (SWALL:P09124) (334 aa) fasta scores: E(): 2.7e-71, 60.06% id in 333 aa, and to Alcaligenes eutrophus glyceraldehyde 3-phosphate dehydrogenase, plasmid CbbGP SWALL:G3PP_ALCEU (SWALL:P50322) (336 aa) fasta scores: E(): 5.1e-112, 84.52% id in 336 aa; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
  
 0.878
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.