node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CA_C0026 | dcd | CA_C0026 | CA_C0025 | Hypothetical protein. | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | 0.946 |
CA_C0026 | pyrE | CA_C0026 | CA_C0027 | Hypothetical protein. | Orotate phosphoribosyltranspherase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.924 |
CA_C0026 | pyrF | CA_C0026 | CA_C2652 | Hypothetical protein. | Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.515 |
CA_C2315 | dcd | CA_C2315 | CA_C0025 | DTDP-4-dehydrorhamnose reductase, rfbD ortholog; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | 0.831 |
ctrA | dcd | CA_C2892 | CA_C0025 | CTP synthase (UTP-ammonia lyase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | 0.926 |
ctrA | nrdD | CA_C2892 | CA_C0480 | CTP synthase (UTP-ammonia lyase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Oxygen-sensitive ribonucleoside-triphosphate reductase nrdD. | 0.908 |
ctrA | nrdD-2 | CA_C2892 | CA_C1209 | CTP synthase (UTP-ammonia lyase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Anaerobic ribonucleotide reductase. | 0.908 |
ctrA | polA | CA_C2892 | CA_C1098 | CTP synthase (UTP-ammonia lyase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | DNA polymerase I, polA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.441 |
ctrA | pyrE | CA_C2892 | CA_C0027 | CTP synthase (UTP-ammonia lyase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Orotate phosphoribosyltranspherase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.687 |
ctrA | pyrF | CA_C2892 | CA_C2652 | CTP synthase (UTP-ammonia lyase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.682 |
dcd | CA_C0026 | CA_C0025 | CA_C0026 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | Hypothetical protein. | 0.946 |
dcd | CA_C2315 | CA_C0025 | CA_C2315 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | DTDP-4-dehydrorhamnose reductase, rfbD ortholog; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. | 0.831 |
dcd | ctrA | CA_C0025 | CA_C2892 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | CTP synthase (UTP-ammonia lyase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.926 |
dcd | dut | CA_C0025 | CA_C1210 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | Deoxyuridine 5'triphosphate nucleotidohydrolase (DUPTase); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.916 |
dcd | dut-2 | CA_C0025 | CA_C1425 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | DUTPase, dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.916 |
dcd | nrdD | CA_C0025 | CA_C0480 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | Oxygen-sensitive ribonucleoside-triphosphate reductase nrdD. | 0.910 |
dcd | nrdD-2 | CA_C0025 | CA_C1209 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | Anaerobic ribonucleotide reductase. | 0.910 |
dcd | polA | CA_C0025 | CA_C1098 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | DNA polymerase I, polA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.492 |
dcd | pyrE | CA_C0025 | CA_C0027 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | Orotate phosphoribosyltranspherase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.912 |
dcd | pyrF | CA_C0025 | CA_C2652 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | Orotidine-5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.508 |