STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CA_C0192Similar to chloromuconate cycloisomerase; Catalyzes the epimerization of L-Ala-D-Glu to L-Ala-L-Glu and has probably a role in the metabolism of the murein peptide, of which L-Ala-D-Glu is a component. Is also able to catalyze the epimerization of L-Ala-D-Asp; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (358 aa)    
Predicted Functional Partners:
CA_C0190
Beta-lactamase.
 
  
 0.841
CA_C0191
Transcriptional regulator, RpiR family.
 
    0.784
murK
Transcriptional regulators of NagC/XylR (ROK) family, sugar kinase; Catalyzes the ATP-dependent phosphorylation of both cell wall (peptidoglycan) amino sugars, N-acetylmuramic acid (MurNAc) and N- acetylglucosamine (GlcNAc), at the 6-hydroxyl group. Neither the non-N- acetylated forms of the cell wall sugars, i.e., glucosamine and/or muramic acid, nor epimeric hexoses or 1,6-anhydro-MurNAc are substrates for the enzyme. May have a role in the rescue of the murein sugars GlcNAc and MurNAc released from muropeptides during cell wall turnover in C.acetobutylicum.
 
    0.715
CA_C0185
Uncharacterized membrane protein, YBBC B.subtilis ortholog.
 
    0.647
CA_C2493
Phospholipase C family protein.
   
    0.580
CA_C0293
MccF-like protein.
 
  
 0.571
CA_C0181
Similar to beta-lactamase.
 
  
 0.506
dnaC
Replicative DNA helicase, DNAC; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
    0.487
CA_C1192
Phage replicative DNA helicase, YorI B.subtilis homolog.
  
    0.485
feoB-2
FeoB-like GTPase, responsible for iron uptake; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
  
    0.468
Your Current Organism:
Clostridium acetobutylicum
NCBI taxonomy Id: 272562
Other names: C. acetobutylicum ATCC 824, Clostridium acetobutylicum ATCC 824, Clostridium acetobutylicum DSM 792, Clostridium acetobutylicum str. ATCC 824, Clostridium acetobutylicum strain ATCC 824
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