STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lycAutolytic lysozime (1,4-beta-N-acetylmuramidase), family 25 of glycosyl hydrolases; peptodoglycan-binding domain. (324 aa)    
Predicted Functional Partners:
CA_C0553
Hypothetical protein, CF-8 family.
  
    0.892
lgt
Propiloprotein diacylglyceryltransferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
     
 0.744
pdxT
Glutamine amidotranspherase (possibly involved in histidine and purine biosinthesis); Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
      
 0.724
CA_C0551
Uncharacterized protein with possible cell attachment and effacing function; Cell-adhesion domain.
  
    0.717
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
   
  
 0.623
uxuA
D-mannonate hydrolase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
   
  
 0.619
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
      
 0.614
pdxS
Predicted phosphate-utilizing enzyme involved in pyridoxine/purine/histidine biosynthesis; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
      
 0.610
lyc-2
N-acetylmuramidase, autolytic enzyme, family 25 of glycosyl hydrolases; peptodoglycan-binding domain.
 
 
 
0.579
CA_C0552
Protein containing cell-adhesion domain.
  
    0.503
Your Current Organism:
Clostridium acetobutylicum
NCBI taxonomy Id: 272562
Other names: C. acetobutylicum ATCC 824, Clostridium acetobutylicum ATCC 824, Clostridium acetobutylicum DSM 792, Clostridium acetobutylicum str. ATCC 824, Clostridium acetobutylicum strain ATCC 824
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