node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CA_C0353 | CA_C2876 | CA_C0353 | CA_C2876 | 2,3-cyclic-nucleotide 2'phosphodiesterase (duplication). | Deoxycytidylate deaminase. | 0.905 |
CA_C0353 | dut | CA_C0353 | CA_C1210 | 2,3-cyclic-nucleotide 2'phosphodiesterase (duplication). | Deoxyuridine 5'triphosphate nucleotidohydrolase (DUPTase); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.900 |
CA_C0353 | dut-2 | CA_C0353 | CA_C1425 | 2,3-cyclic-nucleotide 2'phosphodiesterase (duplication). | DUTPase, dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |
CA_C0353 | tdk | CA_C0353 | CA_C2887 | 2,3-cyclic-nucleotide 2'phosphodiesterase (duplication). | Thymidine kinase; Belongs to the thymidine kinase family. | 0.918 |
CA_C0353 | thyA | CA_C0353 | CA_C3003 | 2,3-cyclic-nucleotide 2'phosphodiesterase (duplication). | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.904 |
CA_C1424 | dut-2 | CA_C1424 | CA_C1425 | Zn-dependent hydrolase, glyoxylase II family. | DUTPase, dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.780 |
CA_C1720 | dut | CA_C1720 | CA_C1210 | Flavoprotein involved in panthothenate metabolism, YLOI B.subtilis ortholog; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Deoxyuridine 5'triphosphate nucleotidohydrolase (DUPTase); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.682 |
CA_C1720 | dut-2 | CA_C1720 | CA_C1425 | Flavoprotein involved in panthothenate metabolism, YLOI B.subtilis ortholog; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | DUTPase, dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.754 |
CA_C2876 | CA_C0353 | CA_C2876 | CA_C0353 | Deoxycytidylate deaminase. | 2,3-cyclic-nucleotide 2'phosphodiesterase (duplication). | 0.905 |
CA_C2876 | dut | CA_C2876 | CA_C1210 | Deoxycytidylate deaminase. | Deoxyuridine 5'triphosphate nucleotidohydrolase (DUPTase); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.933 |
CA_C2876 | dut-2 | CA_C2876 | CA_C1425 | Deoxycytidylate deaminase. | DUTPase, dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.933 |
CA_C2876 | tdk | CA_C2876 | CA_C2887 | Deoxycytidylate deaminase. | Thymidine kinase; Belongs to the thymidine kinase family. | 0.934 |
CA_C2876 | thyA | CA_C2876 | CA_C3003 | Deoxycytidylate deaminase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.937 |
dcd | dut | CA_C0025 | CA_C1210 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | Deoxyuridine 5'triphosphate nucleotidohydrolase (DUPTase); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.916 |
dcd | dut-2 | CA_C0025 | CA_C1425 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | DUTPase, dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.916 |
dcd | nrdD | CA_C0025 | CA_C0480 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | Oxygen-sensitive ribonucleoside-triphosphate reductase nrdD. | 0.910 |
dcd | nrdD-2 | CA_C0025 | CA_C1209 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | Anaerobic ribonucleotide reductase. | 0.910 |
dcd | tdk | CA_C0025 | CA_C2887 | Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | Thymidine kinase; Belongs to the thymidine kinase family. | 0.485 |
dut | CA_C0353 | CA_C1210 | CA_C0353 | Deoxyuridine 5'triphosphate nucleotidohydrolase (DUPTase); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 2,3-cyclic-nucleotide 2'phosphodiesterase (duplication). | 0.900 |
dut | CA_C1720 | CA_C1210 | CA_C1720 | Deoxyuridine 5'triphosphate nucleotidohydrolase (DUPTase); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Flavoprotein involved in panthothenate metabolism, YLOI B.subtilis ortholog; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.682 |