STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CA_C2945Possible phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (324 aa)    
Predicted Functional Partners:
CA_C2834
Uncharacterized conserved protein, YHAD family; Belongs to the glycerate kinase type-1 family.
 
  
 0.936
CA_C2542
FAD/FMN-containing dehydrogenase.
 
 0.932
kdgA
Deoxyphosphogluconate aldolase (gene kdgA).
  
 
  0.905
kdgA-2
2-keto-3-deoxy-6-phosphogluconate aldolase, eda/kdgA.
    
  0.904
CA_C0418
Predicted phosphatase, HAD family.
  
 
  0.903
CA_C2496
Predicted phosphatase of HAD hydrolase superfamily.
  
 
  0.903
CA_C2946
Hypothetical protein.
  
    0.797
cinA
Competence-damage inducible protein, CINA; Belongs to the CinA family.
  
    0.632
CA_C1591
Uncharacterized membrane protein, YCGQ B. subtilis homolog.
   
    0.580
topB
Topoisomerase B; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoi [...]
  
    0.464
Your Current Organism:
Clostridium acetobutylicum
NCBI taxonomy Id: 272562
Other names: C. acetobutylicum ATCC 824, Clostridium acetobutylicum ATCC 824, Clostridium acetobutylicum DSM 792, Clostridium acetobutylicum str. ATCC 824, Clostridium acetobutylicum strain ATCC 824
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.