STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
splBSpore photoproduct (thymine dimer) lyase,radical S-adenosylmethionine superfamily; Experimentally verified as part of mature spore proteome PMID:19542279. (340 aa)    
Predicted Functional Partners:
gpr
Spore endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
   
 0.725
hpdA
Putative 4-hydroxyphenylacetate decarboxylase,activating subunit HpdA; Activation of 4-hydroxyphenylacetate decarboxylase under anaerobic conditions by generation of an organic free radical.
   
  
 0.614
spmA
Spore maturation protein A.
     
 0.564
dapB2
Dihydrodipicolinate reductase 2 (DHPR 2); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
  
  
 0.563
CAJ69029.1
Putative membrane protein; Probably functions as a manganese efflux pump.
  
     0.561
spmB
Spore maturation protein B.
     
 0.542
rlmN
Putative radical SAM-family protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
   
  
 0.526
dapB1
Dihydrodipicolinate reductase 1 (DHPR 1); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
  
  
 0.496
cotCB
Spore-coat protein, manganese catalase; Experimentally verified as part of mature spore proteome PMID:19542279.
  
     0.493
CAJ67098.1
Transcriptional regulator, AraC family.
       0.484
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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