STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rbsRTranscriptional regulator, LacI family. (337 aa)    
Predicted Functional Partners:
rbsK
Ribokinase, pfkB family; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 0.942
CAJ67630.1
Transcriptional regulator, LacI family.
  
    0.775
rbsC
ABC-type transport system, ribose-specific permease; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant PMID:24568651; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.774
rbsB
ABC-type transport system, ribose-specific extracellular solute-binding protein; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant PMID:24568651.
 
  
0.723
rbsA
ABC-type transport system, ribose-specific ATP-binding protein; Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome: up-regulated in Spo0A mutant PMID:24568651.
 
  
 0.721
ptsH
PTS system, HPr protein.
   
 
 0.695
pyk
Pyruvate kinase (PK); Experimentally verified as part of mature spore proteome PMID:19542279; Belongs to the pyruvate kinase family.
    
 
 0.639
RbsC1
ABC-type transport system, sugar-family permease; Belongs to the binding-protein-dependent transport system permease family.
 
  
 0.583
guaA
Fragment of conserved hypothetical protein,DUF111 family; Catalyzes the synthesis of GMP from XMP.
    
   0.562
ribBA
Riboflavin biosynthesis protein ribBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.562
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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