STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAJ67235.1Putative single-strand DNA-binding protein Tn1549-like, CTn2-Orf7. (103 aa)    
Predicted Functional Partners:
CAJ67236.1
Putative conjugative transposon protein Tn1549-like, CTn2-Orf8.
 
  
 0.828
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.814
topB2
DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]
  
 
 0.814
CAJ67237.1
Putative membrane protein Tn1549-like,CTn2-Orf9.
  
    0.744
CAJ67244.1
DNA topoisomerase protein, type IA,Tn1549-like,CTn2-Orf16.
  
 
 0.721
dnaE
DNA polymerase III DnaE subunit alpha.
   
 
 0.713
CAJ67239.1
Putative conjugative transposon protein Tn1549-like, CTn2-Orf11.
  
  
 0.710
CAJ67238.1
Putative conjugative transposon protein Tn1549-like, CTn2-Orf10.
  
    0.708
CAJ67240.1
Putative conjugative transposon protein Tn1549-like, CTn2-Orf12.
  
  
 0.708
CAJ67241.1
Putative conjugative transposon protein Tn1549-like, CTn2-Orf13.
  
  
 0.697
Your Current Organism:
Clostridioides difficile
NCBI taxonomy Id: 272563
Other names: C. difficile 630, Clostridioides difficile 630, Clostridium difficile 630, Clostridium difficile 630 (epidemic type X), Clostridium difficile str. 630, Clostridium difficile strain 630, Peptoclostridium difficile 630
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